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| http://dx.doi.org/10.1136/jcp.29.1.86-e | DOI Listing |
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A Phase I Study of Romidepsin in Combination With Gemcitabine, Oxaliplatin, and Dexamethasone in Patients With Relapsed or Refractory Aggressive Lymphomas Enriched for T-Cell Lymphomas.
Clin Lymphoma Myeloma Leuk
December 2024
Division of Medical Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO. Electronic address:
Introduction: Histone deacetylase inhibitors (HDACi) and combination chemotherapy are independently used to treat relapsed/refractory (R/R) lymphoma. In vitro studies suggest that the addition of HDACi to platinum-based chemotherapy is synergistic.
Patients And Methods: We conducted a phase I study of romidepsin, gemcitabine, oxaliplatin and dexamethasone (Romi-GemOxD) in R/R aggressive lymphomas with an expansion cohort in T-cell lymphomas.
Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women.
Cochrane Database Syst Rev
December 2024
Rehabilitation Teaching and Research Unit, Department of Medicine, University of Otago, Wellington, New Zealand.
Background: Pelvic floor muscle training (PFMT) is a recommended treatment for female stress, urgency, and mixed urinary incontinence. Training varies in exercise type (pelvic floor muscles contracting with and without other muscles), dose, and delivery (e.g.
View Article and Find Full Text PDFNon-steroidal anti-inflammatory drugs for treating symptomatic uncomplicated urinary tract infections in non-pregnant adult women.
Cochrane Database Syst Rev
December 2024
Department of Urology, Freeman Hospital, Newcastle upon Tyne, UK.
Background: Almost half of all women will have at least one symptomatic urinary tract infection (UTI) in their lifetime. Although usually self-remitting, 74% of women contacting a health professional are prescribed an antibiotic, and in rare instances, they may progress to more severe infections. Therefore, the standard of care for the treatment of symptomatic uncomplicated UTIs is oral antibiotic therapy, which aims to achieve symptom resolution and prevent the development of complications such as pyelonephritis.
View Article and Find Full Text PDFCT-guided Left Stellate Ganglion Cryoneurolysis for Refractory Ventricular Arrhythmias.
Radiology
December 2024
From the Department of Radiology, Division of Interventional Radiology (N.L., N.J.R.), Department of Medicine, Division of Interventional Cardiology (Y.R.), and Department of Medicine, Division of Cardiovascular Medicine (Y.R., G.S., M.G.), UMass Memorial Medical Center and Chan Medical School, 55 Lake Ave N, S2-817A, Worcester, MA 01655; Department of Radiology and Imaging Sciences, Division of Interventional Radiology and Image-Guided Medicine, Emory University School of Medicine, Atlanta, Ga (J.K.); Division of Cardiology, Division of Electrophysiology, Emory Heart & Vascular Center at Saint Joseph's Hospital, Atlanta, Ga (A.M.P., C.M.T.); Department of Heart Failure/Transplant Cardiology, Piedmont Heart Institute, Piedmont Healthcare, Atlanta, Ga (D.W.M.); and Franklin College of Arts and Sciences, University of Georgia, Athens, Ga (F.J.P.).
Background Ventricular arrhythmias (VAs), including ventricular tachycardia and ventricular fibrillation, present substantial therapeutic challenges due to their high morbidity, mortality, and increasing prevalence. Current treatments often prove infeasible or inadequate in patients with refractory VAs. Purpose To evaluate the safety and effectiveness of CT-guided left stellate ganglion cryoneurolysis (SGC) in the treatment of refractory VAs.
View Article and Find Full Text PDFEvaluating Readability and Reliability of Online Information Provided by Pancreas Transplant Centers in the United States.
Clin Transplant
December 2024
Department of Surgery, Transplantation Center, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Background: The decision of proceeding with a pancreas transplant (PTx) is a complex one, and patient education is important to allow transplant candidates to make an informed and autonomous decision. In this study, we assessed the readability and reliability of online information provided by PTx centers in the United States.
Methods: Websites of PTx centers active between 2022 and 2023 were searched for patient information on pancreas transplantation.
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