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Similar Publications

Sudden cardiac death associated with fatty liver disease.

Int J Cardiol Heart Vasc

February 2025

Center for Cardiac Arrest Prevention, Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, CA, USA.

Background: Fatty liver disease or steatotic liver disease (SLD) affects 25% of the global population and has been associated with heart disease. However, there is a lack of postmortem studies in the context of sudden cardiac death (SCD).

Objectives: To investigate the relationship between SLD and SCD.

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Introduction According to the World Health Organization (WHO), cardiovascular diseases are the leading cause of death globally, accounting for approximately 17 million deaths annually, with sudden cardiac arrest (SCA) as a significant contributor to this alarming statistic. SCA, the abrupt loss of heart function, is a critical medical emergency that requires early recognition and immediate cardiopulmonary resuscitation (CPR) for the effective resuscitation of victims. Various studies have shown a low level of knowledge regarding CPR in the community.

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Background: There is a shortage of patients with hypertrophic cardiomyopathy (HCM) with concurrent coronary artery disease (CAD), and the influence of CAD on the prognosis of patients with HCM is uncertain. This real-world cohort study was conducted to evaluate the prognosis of patients with patients with CAD.

Methods: This cohort study of patients with HCM was conducted from May 2003 to September 2021.

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Ventricular Depolarization Abnormalities and Their Role in Cardiac Risk Stratification - A Narrative Review.

Rev Cardiovasc Med

January 2025

Department of Cardiovasculair Sciences, KU Leuven, 3000 Leuven, Belgium.

Ventricular depolarization refers to the electrical activation and subsequent contraction of the ventricles, visible as the QRS complex on a 12-lead electrocardiogram (ECG). A well-organized and efficient depolarization is critical for cardiac function. Abnormalities in ventricular depolarization may indicate various pathologies and can be present in all leads if the condition is general, or in a subgroup of anatomically contiguous leads if the condition is limited to the corresponding anatomic location of the heart.

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Dilated cardiomyopathy (DCM) is the ultimate manifestation of the myocardial response to various genetic and environmental changes and is characterized mainly by impaired left ventricular systolic and diastolic function. DCM can ultimately lead to heart failure, ventricular arrhythmia (VA), and sudden cardiac death (SCD), making it a primary indication for heart transplantation. With advancements in modern medicine, several novel techniques for evaluating myocardial involvement and disease severity from diverse perspectives have been developed.

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