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Growing a thriving international community for small-angle scattering through collaboration.
J Appl Crystallogr
August 2021
School of Life and Environmental Sciences, The University of Sydney, Building G08, Camperdown, NSW 2006, Australia.
Small-angle scattering emerged as a tool for studying noncrystalline structures from early observations around 1930 that there was a relationship between the extent of the scattering and the size of the scattering object. André Guinier, a leading figure in the development of the field, noted in his summary findings from the first Conference on Small Angle Scattering in 1958 that the technique would be of value to study 'submicroscopical inhomogeneities' and further provided a means of 'observation [that had] in the past restricted the field of application of the X-ray method.' In 1965 the first of what became a highly successful series of Small-Angle Scattering (SAS) meetings held approximately every three years took place in Syracuse, NY, USA, and many of these ongoing meetings published their proceedings and highlights in the International Union of Crystallography (IUCr) .
View Article and Find Full Text PDFGolgi function and dysfunction in the first COG4-deficient CDG type II patient.
Hum Mol Genet
September 2009
and Department for Molecular and Developmental Genetics, Laboratory for Membrane Trafficking, Center for Human Genetics, University of Leuven VIB, B-3000 Leuven, Belgium.
The conserved oligomeric Golgi (COG) complex is a hetero-octameric complex essential for normal glycosylation and intra-Golgi transport. An increasing number of congenital disorder of glycosylation type II (CDG-II) mutations are found in COG subunits indicating its importance in glycosylation. We report a new CDG-II patient harbouring a p.
View Article and Find Full Text PDFDielectrophoretic manipulation of DNA.
IEE Proc Nanobiotechnol
November 2003
Fraunhofer Institut for Biomedical Engineering, Department of Molecular Bioanalytics and Bioelectronics, Bergholz-Regbrücke, Germany.
The characterisation and spatial manipulation of cells by AC electrokinetic methods such as dielectrophoresis and electrorotation is well established. However, applications to submicroscopical objects like viruses and molecules have been rare. Only recently has the number of such studies risen more quickly due to the availability of suitable electrodes and a growing need for single molecule techniques.
View Article and Find Full Text PDFGluten sensitivity and 'normal' histology: is the intestinal mucosa really normal?
Dig Liver Dis
November 2003
Section of Anatomy and Histology, Department of Morphological and Biomedical Sciences, University of Verona, Verona, Italy.
Background: Early pathogenetic events of gluten intolerance may be overlooked in patients with serologic markers of celiac disease and normal intestinal mucosa by both conventional histology and immunohistochemistry.
Aims: To investigate if a submicroscopical damage of the absorptive cell surface was associated with developing gluten sensitivity.
Patients And Methods: Duodenal biopsies of seven subjects with positive anti-endomysial antibodies and normal histology underwent ultrastructural evaluation of the epithelial surface by means of both scanning and transmission electron microscopy.
Submicroscopic mathematical evaluation of spermatozoa in assisted reproduction. 4. The bovine fertilization (Notulae seminologicae 10).
J Submicrosc Cytol Pathol
October 1997
Institute of General Biology, University of Siena, Italy.
In this paper we apply a modification of the formula of Baccetti et al. (1995) in the evaluation of submicroscopical characteristics of bull spermatozoa used in assisted reproduction. In the present experiment sperm quality is proposed as a useful parameter in predicting the success of fertilization.
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