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A 4-year cohort study of the effects of PNPLA3 rs738409 genotypes on liver fat and fibrosis and gut microbiota in a non-fatty liver population.
Environ Health Prev Med
March 2025
Department of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine.
Background: Many factors are associated with the development and progression of liver fat and fibrosis; however, genetics and the gut microbiota are representative factors. Moreover, recent studies have indicated a link between host genes and the gut microbiota. This study investigated the effect of patatin-like phospholipase domain-containing 3 (PNPLA3) rs738409 (C > G), which has been reported to be most involved in the onset and progression of fatty liver, on liver fat and fibrosis in a cohort study related to gut microbiota in a non-fatty liver population.
View Article and Find Full Text PDFCorrelation between periodontal status, whole salivary interleukin-1beta levels and oral yeasts carriage among individuals with varying ranges of body mass index.
Acta Odontol Scand
March 2025
Department of General Dental Practice, Faculty of Dentistry, Kuwait University, Safat, Kuwait.
The aim was to assess the correlation between periodontal status, whole salivary interleukin-1 beta (IL-1β) levels and oral yeasts carriage (OYC) among individuals with varying ranges of body mass index (BMI). Material and method: The weight, waist circumference (WC), and height of individuals were assessed. Participants were categorized into three groups: Group-1 - normal weight (18.
View Article and Find Full Text PDFComposite Pheochromocytoma-Paraganglioma With Ganglioneuroma: A Dual-Center Clinical Experience.
J Endocr Soc
March 2025
Division of Endocrinology and Metabolism, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Context: Cells derived from neural crest populate several organs. A particular precursor cell, sympathogonia, gives rise to pheochromoblasts and neuroblasts. Due to common origin, tumors originating from pheochromoblasts, such as pheochromocytoma (PHEO) and paraganglioma (PGL), may rarely coexist with ganglioneuroma (GN).
View Article and Find Full Text PDFUtility of underwater endoscopic mucosal resection combined with a protruding anchor by saline injection for superficial non-ampullary duodenal tumors: a retrospective study in Japan.
Clin Endosc
March 2025
Division of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.
Background/aims: Underwater endoscopic mucosal resection (UEMR) is the standard resection method for superficial non-ampullary duodenal tumors (SNADETs). We developed a novel UEMR technique that creates an anchor by protruding the distal fold with a saline injection (UEMR-A). The aim of this study was to clarify the usefulness of UEMR-A compared to conventional UEMR (UEMR-C).
View Article and Find Full Text PDFProspective assessment of learning curve and impact of intensive versus progressive training in colonoscopy competence among French residents.
BMC Med Educ
March 2025
Gastroenterology Unit, CHU de Montpellier, Montpellier Univ, MUSE, Montpellier, France.
Backgrounds: There are no existing data in the literature on the learning curve of French interns in colonoscopy or on the comparison between different frequencies of colonoscopy training modalities. We aimed to assess the number of procedures required for French residents in hepatogastroenterology to achieve competency in colonoscopy.
Methods: The primary outcome was achieving greater than 90% cecal intubation rate (CIR90) competency using the Learning Curve-Cumulative Summation (LC-CUSUM) method.
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