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J Trauma Acute Care Surg
December 2024
From the Department of Surgery, University of Cincinnati, Cincinnati, Ohio.
Background: Red blood cell (RBC) aggregation can be initiated by calcium and tissue factor, which may independently contribute to microvascular and macrovascular thrombosis after injury and transfusion. Previous studies have demonstrated that increased blood storage duration may contribute to thrombotic events. The aims of this study were to first determine the effect of blood product components, age, and hematocrit (HCT) on the aggregability of RBCs, followed by measurement of RBC aggregability in two specific injury models including traumatic brain injury (TBI) and hemorrhagic shock.
View Article and Find Full Text PDFEar Hear
December 2024
Center for Hearing Research, Boys Town National Research Hospital, Omaha, Nebraska, USA.
Objectives: To investigate the influence of frequency-specific audibility on audiovisual benefit in children, this study examined the impact of high- and low-pass acoustic filtering on auditory-only and audiovisual word and sentence recognition in children with typical hearing. Previous studies show that visual speech provides greater access to consonant place of articulation than other consonant features and that low-pass filtering has a strong impact on perception on acoustic consonant place of articulation. This suggests visual speech may be particularly useful when acoustic speech is low-pass filtered because it provides complementary information about consonant place of articulation.
View Article and Find Full Text PDFChaos
January 2025
Department of Mathematics, National Institute of Technology Silchar, Silchar, Assam 788010, India.
This study introduces a five-compartment model to account for the impacts of vaccination-induced recovery and nonlinear treatment rates in settings with limited hospital capacity. To reflect real-world scenarios, the model incorporates multiple reinfections in both vaccinated and recovered groups. It reveals a range of dynamics, including a disease-free equilibrium and up to six endemic equilibria.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Nursing and Podiatry, University of Malaga, Malaga, Spain.
Cellular therapy is a promising treatment option for Peripheral Arterial Disease (PAD). Different cell types can be used to regenerate and repair tissues affected by PAD. Many studies have proposed the use of stem cells, such as mesenchymal stem cells, or even mononuclear cells isolated from peripheral blood or bone marrow, to treat PAD.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Microbiology, Immunology and Parasitology, Laboratory of Protozoology, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
In Brazil, Visceral Leishmaniases is caused by Leishmania infantum, and domestic dogs are the main reservoirs in its urban transmission cycle. As an alternative to euthanizing dogs, miltefosine has been used to treat canine visceral leishmaniasis since 2016. In this study, we have assessed the efficacy of miltefosine for treating canine visceral leishmaniasis in a new endemic area through follow-up of naturally infected dogs was evaluated.
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