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EEG reveals brain network alterations in chronic aphasia during natural speech listening.
Sci Rep
January 2025
Experimental Oto-Rhino-Laryngology, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Belgium.
Aphasia is a common consequence of a stroke which affects language processing. In search of an objective biomarker for aphasia, we used EEG to investigate how functional network patterns in the cortex are affected in persons with post-stroke chronic aphasia (PWA) compared to healthy controls (HC) while they are listening to a story. EEG was recorded from 22 HC and 27 PWA while they listened to a 25-min-long story.
View Article and Find Full Text PDFThe neurocognitive correlates of DTI indicators of white matter disorganization in pediatric moderate-to-severe traumatic brain injury.
Front Hum Neurosci
October 2024
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.
Introduction: Neuroimaging has expanded our understanding of pediatric brain disorders in which white matter organization and connectivity are crucial to functioning. Paralleling the known pathobiology of many neurodevelopmental disorders, traumatic brain injury (TBI) in childhood can alter trajectories of brain development. Specifically, diffusion tensor imaging (DTI) studies in TBI have demonstrated white matter (WM) abnormalities that suggest microstructural disruptions that may underlie atypical neurodevelopment.
View Article and Find Full Text PDFDelayed cyst formation after radiosurgery for arteriovenous malformation: A case report and critical review.
Surg Neurol Int
October 2024
Neurosurgery Department, Unidade Local de Saúde de São João (ULS São João), Oporto, Portugal.
Background: Stereotactic radiosurgery (SRS) is a validated treatment option for cerebral arteriovenous malformations (AVMs), even if a greater knowledge of its potential delayed complications is still being acquired.
Case Description: A 49-year-old man suffered multiple episodes of cerebral hemorrhage in an approximate 10-year follow-up interval in the context of a left central core AVM with deep venous drainage into the internal cerebral veins (Spetzler Martin Grade 4) despite being treated with gamma knife radiosurgery at two separate timepoints, and with an almost complete obliteration confirmed. Approximately 10 years after the first radiosurgery treatment, he developed severe motor aphasia, Grade 3 right hemiparesis, progressive confusion, and memory deficits.
Correlation Between Intraoperative Near-infrared Spectroscopy Values and Neurologic Outcomes in Patients Undergoing Total Aortic Arch Replacement Using the Frozen Elephant Trunk Technique.
J Cardiothorac Vasc Anesth
January 2025
Clinic for Cardiac and Vascular Surgery, Department University Heart Center Freiburg - Bad Krozingen, University Clinic Freiburg, Freiburg, Germany; Faculty of Medicine, Albert Ludwigs University Freiburg, Freiburg. Electronic address:
Objective: To correlate intraoperative near-infrared spectroscopy (NIRS) values with neurologic outcomes in patients undergoing total aortic arch replacement using the frozen elephant trunk (FET) technique.
Design: Retrospective, single-center registry study using a two-way repeated-measures analysis of variance.
Setting: Between November 2013 and December 2023, 427 patients were treated for acute and chronic aortic pathologies using the FET procedure.
Behavioral disorders in multiple sclerosis: a comprehensive review.
J Neural Transm (Vienna)
January 2025
Institute of Clinical Neurobiology, Alberichgasse 5/13, Vienna, A-1150, Austria.
Article Synopsis
- Multiple sclerosis (MS) is a complex autoimmune disease affecting the central nervous system, leading to symptoms such as inflammation, demyelination, and cognitive impairment, with behavioral changes often emerging early and escalating with disease progression.
- About 30 to 80% of MS patients experience behavioral disorders such as anxiety, aggression, and executive dysfunction, which can combine with depression but are generally not linked to motor skill declines.
- Neuroimaging studies indicate that MS is associated with specific brain changes and that therapeutic interventions like psychology, behavior modification, and exercise show promise in managing these symptoms and improving patients' quality of life.
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