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An Unusual Case of Acute Abdomen With Jaundice.
Cureus
December 2024
Cardiology, University Clinics of Kinshasa, Kinshasa, COD.
Adrenocortical carcinomas are rare but aggressive tumors that are frequently discovered as incidentalomas. Secretory tumors often lead to endocrine abnormalities, namely cushingoid features, virilization, or feminization. Non-functioning tumors, on the other hand, can be completely dormant with an insidious course or cause malaise, weight loss, abdominal pain, etc.
View Article and Find Full Text PDFThe Potential Health Risks and Benefits of Progesterone in the Transgender Woman Population-A Narrative Review.
J Clin Med
November 2024
Department of Gynecological Endocrinology, Clinical Hospital of Duchess Anna Mazowiecka, Medical University of Warsaw, 2 Karowa Street, 00-315 Warsaw, Poland.
Introduction: Currently, progesterone is notably absent from conventional feminizing hormone therapies for transgender women. Anecdotal reports indicate the potential for health advantages following the incorporation of progesterone into treatment regimens. The primarily female hormone, progesterone naturally surges in women during the menstrual luteal phase.
View Article and Find Full Text PDFMusculoskeletal Pain and Right Leg Paresthesia Revealed as Large Ovarian Mucinous Cystadenoma: A Case Report.
Am J Case Rep
September 2024
Obstetrics and Gynecology Clinic, K.M.P THERAPIS Paphos Medical Center, Paphos, Cyprus.
Article Synopsis
- * Small ovarian cystadenomas are often asymptomatic but can cause discomfort and other symptoms as they grow, including abdominal pain and urinary issues.
- * A case study of a 31-year-old woman highlights how a large mucinous cystadenoma in the sacrococcygeal area can be mistaken for musculoskeletal issues, underscoring the need for early diagnosis to ensure proper treatment and symptom relief.
Feminization of social play behavior depends on microglia.
bioRxiv
August 2024
Department of Pharmacology, Physiology and Drug Development and University of Maryland Medicine - Institute for Neuroscience Discovery (UM-MIND), University of Maryland School of Medicine, Baltimore, MD 21201.
Many sex differences in brain and behavior are established developmentally by the opposing processes of feminization and masculinization, which manifest following differential steroid hormone exposure in early life. The cellular mechanisms underlying masculinization are well-documented, a result of the fact that it is steroid-mediated and can be easily induced in newborn female rodents via exogenous steroid treatment. However, the study of feminization of particular brain regions has largely been relegated to being "not masculinization" given the absence of an identified initiating trigger.
View Article and Find Full Text PDFSoma-germline communication drives sex maintenance in the testis.
Natl Sci Rev
August 2024
Shenzhen Key Laboratory of Synthetic Genomics, Guangdong Provincial Key Laboratory of Synthetic Genomics, Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
In adult gonads, disruption of somatic sexual identity leads to defective gametogenesis and infertility. However, the underlying mechanisms by which somatic signals regulate germline cells to achieve proper gametogenesis remain unclear. In our previous study, we introduced the ( ) mutant testis phenotype as a valuable model for investigating the mechanisms underlying sex maintenance.
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