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The Effects of Self-Monitoring Using a Smartwatch and Smartphone App on Stress Awareness, Self-Efficacy, and Well-Being-Related Outcomes in Police Officers: Longitudinal Mixed Design Study.
JMIR Mhealth Uhealth
January 2025
Department of Learning and Workforce Development, The Netherlands Organisation for Applied Scientific Research, Soesterberg, Netherlands.
Background: Wearable sensor technologies, often referred to as "wearables," have seen a rapid rise in consumer interest in recent years. Initially often seen as "activity trackers," wearables have gradually expanded to also estimate sleep, stress, and physiological recovery. In occupational settings, there is a growing interest in applying this technology to promote health and well-being, especially in professions with highly demanding working conditions such as first responders.
View Article and Find Full Text PDFInvestigate physiological and psychological responses to environment scenes, elements and components in different urban settings.
Sci Rep
January 2025
Institute of Geography, School of GeoSciences, University of Edinburgh, Edinburgh, UK.
Research has proved a close relationship between environments and physiological as well as psychological responses. However, existing research based on neuroscience experiments demonstrated a clear dichotomy between natural and built environments in the selection of exposure settings. There is very limited research analyzing and comparing the effects of different urban environments on individual psychological health.
View Article and Find Full Text PDFEPIDURAL ADMINISTRATION OF TRAMADOL DOES NOT PROVIDE SUFFICIENT INTRAOPERATIVE ANALGESIA FOR ELECTIVE OVARIOHYSTERECTOMY IN HEALTHY CATS.
Top Companion Anim Med
January 2025
Department of Small Animal Clinic, Centre of Rural Sciences, Federal University of Santa Maria (UFSM), Rio Grande do Sul State, Brazil.
Few studies today address trans-operative analgesia provided by tramadol without local anesthetics for intra-abdominal procedures. The objective of this study was to assess the efficacy of trans-operative analgesia provided by epidurally administered tramadol in cats undergoing elective ovariohysterectomy. For this purpose, 16 healthy queens were randomly assigned to participate in one of two groups: GC, control group, 0.
View Article and Find Full Text PDFSMARCA2 protein: Structure, function and perspectives of drug design.
Eur J Med Chem
January 2025
Key Laboratory for Green Chemical Process of Ministry of Education, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan, 430205, P. R. China. Electronic address:
SMARCA2 is an ATPase that regulates chromatin structure via ATP pathways, controlling cell division and differentiation. SMARCA2's bromodomain and ATPase domain, crucial for chromatin remodeling and cell regulation, are therapeutic targets in cancer treatment. This review explores the role of SMARCA2 in cancer development by studying its protein structure and physiological functions.
View Article and Find Full Text PDFAim: Human carbonic anhydrases (hCAs) are involved in many physiological processes including respiration, pH control, ion transport, bone resorption, and gastric fluid secretion. Recently, CA IX and CA XII have been studied for their role in cancer diseases, motivating the design of inhibitors of these isoforms.
Material And Method: Here, we used the tail approach to design a new series of monoaryl () and bicyclic () benzensulfonamide derivatives CA IX and CA XII inhibitors.
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