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Fibrotic hypersensitivity pneumonitis (HP) has a poor prognosis when no antigen is identified, which occurs in many cases. We present a case of HP due to foam exposure in bedding, an unrecognised cause of HP. A woman was referred for dyspnoea and cough.

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Hypersensitivity pneumonitis associated with inhalation of spores (lycoperdonosis) in a 3-month-old English setter dog in Quebec.

Can Vet J

June 2024

Département des sciences cliniques, Faculté de médecine vétérinaire, Université de Montréal, 3200 rue Sicotte, Saint-Hyacinthe, Québec J2S 2M2 (Lécuyer, Auffret, Martin, Letendre, Finck); Département de pathologie et de microbiologie, Faculté de médecine vétérinaire, Université de Montréal, 3200 rue Sicotte, Saint-Hyacinthe, Québec J2S 2M2 (Corrales Mesa, Bédard); Centre Vétérinaire Laval, 4530 A. 440, Laval, Québec H7T 2P7 (Duval).

Article Synopsis
  • A 3-month-old female English setter in Quebec presented with severe respiratory distress, leading to the discovery of fungal spores in its lungs during bronchoalveolar lavage.
  • The dog’s health rapidly worsened within 24 hours and it was euthanized; post-mortem tests confirmed the presence of lycoperdonosis, a fungal infection from inhaling mushroom spores.
  • This is the first documented case of lycoperdonosis in eastern Canada, highlighting the need for veterinarians to consider spore inhalation in similar acute respiratory cases and to take detailed patient histories.
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Article Synopsis
  • Hypersensitivity pneumonitis (HP) is a lung disease resulting from inflammation and scarring caused by long-term exposure to certain antigens, leading to type 3 and type 4 hypersensitivity reactions.
  • Clinically, HP presents with symptoms like shortness of breath and wheezing; tests reveal restrictive lung patterns and characteristic CT scan findings.
  • Current preventive measures focus on avoiding antigens, while treatments include prednisone for acute cases and mycophenolate mofetil for chronic cases, highlighting the need for more research on MMF's effectiveness in fibrosing HP.
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Hypersensitivity Pneumonitis-like Histological Findings Secondary to SARS-COV-2 Pneumonia.

Arch Bronconeumol

July 2024

Servei de Pneumologia, Hospital Universitari Vall d'Hebron, Departament de Medicina, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain; Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain; CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, Spain. Electronic address:

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Can concentrated growth factor prevent postoperative complications of impacted third molar surgery? A split-mouth randomized double-blind trial.

Clin Oral Investig

April 2024

Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, 301, Middle Yanchang Road, Shanghai, 200072, China.

Objectives: The purpose of the present study was to evaluate the effect of concentrated growth factor (CGF) on prevention of postoperative complications in the impacted third molar extraction.

Materials And Methods: A total of 25 healthy patients with symmetrical bilaterally impacted third molars (50 extraction sites) were enrolled in this split-mouth, randomized, double-blind clinical trial. Third molar extractions were performed in both sites of the mandible at the same appointment.

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