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Evaluation of Stress Ulcer Prophylaxis in Pediatric General Medicine Patients After Transfer From the Intensive Care Unit and at Discharge.
J Pediatr Pharmacol Ther
December 2024
Department of Pharmacy (LL, SL, JWB), Texas Children's Hospital, Houston, TX.
Objectives: The primary aim of this study was to determine continuation rates of stress ulcer prophylaxis (SUP) upon transfer from a pediatric intensive care unit (PICU) to a general medicine unit and upon hospital discharge. The secondary aim was to identify patient characteristics or concomitant medications that were associated with continuation of SUP at transfer from the PICU.
Methods: This retrospective chart review included patients who were initiated on acid suppression for SUP in the PICU between June 2021 and May 2022 and subsequently transferred to a general medicine unit prior to discharge.
Improved Technique Reduce Lower Limb Complications After the Traditional No-Touch Technique for Vein Graft Harvesting: A Single-Center Retrospective Historical Controlled Study.
J Multidiscip Healthc
November 2024
Department of Physiology, Hebei Medical University, Shijiazhuang, 050000, People's Republic of China.
Objective: The employment of the no-touch technique in harvesting the great saphenous vein (GSV) for coronary artery bypass grafting has been associated with a significant improvement in clinical patency rates. Despite these advantages, such grafts may predispose patients to complications in the lower limbs. This study endeavors to evaluate the incidence of complications in the lower extremities by deploying an enhanced protocol for the no-touch harvesting technique.
View Article and Find Full Text PDFProton pump inhibitors are detrimental to overall survival of patients with glioblastoma: Results from a nationwide real-world evidence database.
Neurooncol Pract
December 2024
xCures Inc., Oakland, California, USA.
Background: Proton pump inhibitors (PPIs) are often prescribed to manage corticosteroid-induced gastrointestinal toxicity during glioblastoma (GBM) treatment, but were recently identified as strong inducers of aldehyde dehydrogenase-1A1 (ALDH1A1). ALDH1A1 is a primary metabolic enzyme impacting the outcome of chemotherapy, including temozolomide. High expression of ALDH1A1 is associated with poor prognosis in multiple cancers, suggesting PPIs may have a negative impact on survival.
View Article and Find Full Text PDFFatal rhabdomyolysis and fulminant myocarditis with malignant arrhythmias after one dose of ipilimumab and nivolumab.
Immunotherapy
January 2025
Department of Internal Intensive Medicine, General Hospital Celje, Celje, Slovenia.
Immune checkpoint inhibitors (ICIs) related myocarditis is a rare complication of modern immunotherapy. It can present as an asymptomatic subclinical condition or full-blown fulminant myocarditis with malignant arrythmias and cardiogenic shock. Myositis/rhabdomyolysis and/or myasthenic symptoms can be present concomitantly.
View Article and Find Full Text PDFAgri-solar water pumping design, energy, and environmental analysis: A comprehensive study in tropical humid climate.
Heliyon
November 2024
Faculty of Mechanical and Automotive Engineering Technology, Universiti Malaysia Pahang Al Sultan Abdullah, 26600, Pekan, Pahang, Malaysia.
Agrivoltaics is an innovative approach where solar energy, water, land and biodiversity are integrated into the same area to maximize resource utilization for sustainable development, also known as Agrivoltaism. The combination of solar water pumping and agri-solar has led to the development of a new generation of irrigation systems that are highly sustainable and efficient. Agri-solar water pumping can irrigate crops, feed livestock, clean solar modules, cool the PV system, generate energy, store water, and provide community drinking water.
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