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Smaller-incision new-generation implantable miniature telescope in late-stage age-related macular degeneration: 6 month outcomes.
Heliyon
January 2025
Ophthalmology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Purpose: To evaluate the intermediate-term visual and safety outcomes of the small-incision second-generation implantable miniature telescope (SING IMT) in patients with late-stage age-related macular degeneration (AMD) at 6 months post-surgery.
Design: Retrospective cohort study.
Methods: Medical records of patients implanted with the SING IMT at two sites in Italy were reviewed.
Fibrosis in age-related neovascular macular degeneration in the anti-VEGF era.
Eye (Lond)
December 2024
Honorary and Emerita Professor of Ophthalmology, Queens University of Belfast, Belfast, UK.
The natural history of neovascular age-related macular degeneration (nAMD) leads to scarring and loss of vision. Since the advent of anti-VEGF therapies, which are very effective for controlling exudation, large disciform scars are rarely encountered in the clinic. However long term studies show that smaller and less severe fibrotic scars are not uncommon and develop over time despite optimal treatment.
View Article and Find Full Text PDFEarly Choriocapillaris Loss in a Porcine Model of RPE Cell Debridement Precedes Pathology That Simulates Advanced Macular Degeneration.
Invest Ophthalmol Vis Sci
April 2024
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States.
Purpose: No large-mammal surgical models exist for geographic atrophy (GA), choroidal neovascularization (CNV), and pachychoroidal vascular remodeling. Our goal was to develop a porcine RPE debridement model of advanced macular degeneration to study photoreceptor cell loss and choroidal remodeling.
Methods: Seven 2-month-old female domestic pigs were used for this study.
Functional and structural characteristics in patients with type 3 macular neovascularisation treated with anti-VEGF. Three-year results in real world settings.
Eye (Lond)
June 2024
Department of Ophthalmology, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD, Hampshire, United Kingdom.
Background: To evaluate the long-term anatomical and functional outcomes of anti-Vascular Endothelial Growth Factor intravitreal injections (anti-VEGF IVI) in patients with type 3 macular neovascularisation (MNV) in real-world settings.
Methods: Retrospective review of patients with type 3 MNV who received anti-VEGF IVI between 2013 and 2020. Primary outcomes were best corrected visual acuity (BCVA) and central macular thickness (CMT).
Peripheral Hemorrhagic Chorioretinopathy: Differentiating Features from Choroidal Melanoma.
Ocul Oncol Pathol
August 2023
Cleveland Clinic, Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland, Ohio, USA.
Introduction: Peripheral exudative hemorrhagic chorioretinopathy (PEHCR) is one of the leading mimickers of choroidal melanoma because of overlapping features with choroidal melanoma that make the distinction between these two entities difficult.
Methods: To identify nonoverlapping diagnostic features between PEHCR and choroidal melanoma, a retrospective study of 80 patients (80 eyes); 40 patients (40 eyes) with PEHCR; and 40 patients (40 eyes) with choroidal melanoma was conducted. Ophthalmoscopic and imaging features of PEHCR and choroidal melanoma were compared.
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