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Adverse Prehospital Events and Outcomes After Traumatic Brain Injury.
JAMA Netw Open
January 2025
Department of Emergency Medicine, The Ohio State University, Columbus.
Importance: While national guidelines recommend avoidance of hypoxia, hypotension, and hypocarbia in the prehospital care of traumatic brain injury (TBI), limited data validate the association of these adverse physiologic events with TBI outcomes.
Objective: To validate the associations of prehospital hypoxia, hypotension, and hypocarbia with TBI outcomes in a US national trauma network.
Design, Setting, And Participants: This cohort study examined data from 8 level I trauma centers and their affiliated ground and air emergency medical services (EMS) agencies in the Linking Investigations in Trauma and Emergency Services (LITES) Network from January 1, 2017, to June 30, 2021.
Corticosteroids in Cardiogenic Shock: A Retrospective Analysis of the Medical Information Mart for Intensive Care-IV Database.
Crit Care Explor
February 2025
Division of Critical Care Medicine, Department of Medicine, McMaster University, Hamilton, ON, Canada.
Importance: While corticosteroid administration in septic shock has been shown to result in faster shock reversal and lower short-term mortality, the role of corticosteroids in the management of cardiogenic shock (CS) remains unexplored.
Objectives: Determine the impact of corticosteroid administration on 90-day mortality (primary outcome) in patients admitted to a critical care unit with CS.
Design, Setting, And Participants: In this retrospective cohort study, we used the critical care database of Medical Information Mart for Intensive Care-IV, and included all adult patients diagnosed with CS excluding repeated admissions, patients with adrenal insufficiency, those receiving baseline corticosteroids, and those requiring extracorporeal life support.
Impact of Delayed Surgery on Local Colorectal Neuroendocrine Tumors: Is Surveillance a Feasible Option?
Ann Surg Oncol
January 2025
Department of Surgery, Weill Cornell Medicine, New York, NY, USA.
Background: Guidelines for some pancreatic neuroendocrine tumors (NETs) have shifted towards active surveillance given the indolent nature of this malignancy. We sought to assess the safety of delayed surgery on colorectal NETs as a surrogate for surveillance.
Methods: Resected, stage I, well-differentiated colorectal primary NETs included in the Surveillance, Epidemiology, and End Results Program from 2010 to 2020 were included.
Causes of hospitalization and mortality in persons with epilepsy: The EpiLink Bologna cohort, Italy.
Eur J Neurol
February 2025
Full Member of the European Reference Network for Rare and Complex Epilepsies (EpiCARE), IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Background: Epilepsy significantly impacts on morbidity and mortality. Understanding hospitalization and mortality risks in persons with epilepsy (PWE) is essential for improving healthcare strategies. We aimed to investigate the risk and causes of hospitalization and mortality in PWE compared to a matched general population cohort.
View Article and Find Full Text PDFAssociation between dairy product intake and prevalence of dental caries in 3-year-old Japanese children.
J Pediatr Gastroenterol Nutr
January 2025
Department of Epidemiology and Public Health, Ehime University Graduate School of Medicine, Ehime, Japan.
Objectives: Epidemiologic evidence on the association between intake of milk and dairy products and dental caries is limited, particularly in Asia. This cross-sectional study examined the association between the consumption of milk and dairy products and dental caries among Japanese children aged 3 years.
Methods: The study subjects were 6221 children.
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