Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Tuberous sclerosis: a survey in the canton of Vaud, Switzerland.
Front Med (Lausanne)
December 2024
Department of Medicine, Service of Nephrology, Fribourg State Hospital, Fribourg, Switzerland.
Aim Of The Study: Tuberous sclerosis complex (TSC) is a genetic and multisystemic disorder that affects between 1/6'000 and 1/10'000 of newborns. Clinical criteria and/or genetic analysis establish the diagnosis. The mechanistic target of rapamycin (mTOR) inhibitors everolimus or sirolimus reduce the severity of several TSC-related clinical traits.
View Article and Find Full Text PDFPrimary thymic mucosa-associated lymphoid tissue (MALT) lymphoma with Sjogren's syndrome and diffuse cystic lung disease: a complex respiratory presentation of a multifaceted autoimmune disease.
BMJ Case Rep
December 2024
University of New South Wales Faculty of Medicine, Sydney, New South Wales, Australia
Article Synopsis
- - Mucosa-associated lymphoid tissue (MALT) lymphoma is a rare B-cell lymphoma that can affect various organs, and patients with Sjögren's syndrome (SjS) have significantly higher risks of developing it.
- - A case study is presented of primary thymic MALT lymphoma found incidentally during routine chest imaging, alongside cystic lung disease, primarily observed in women with SjS.
- - Imaging techniques revealed a large mass in the mediastinum and numerous pulmonary cysts; the diagnosis was confirmed via biopsy, and treatment improved lung function, emphasizing the link between SjS and MALT lymphoma's lung manifestations.
Features of Lung Cysts in Birt-Hogg-Dubé Syndrome from Patients with Multiple Lung Cysts.
Tuberc Respir Dis (Seoul)
November 2024
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 04763, Republic of Korea.
Article Synopsis
- High-resolution chest CT scans are essential for diagnosing Birt-Hogg-Dubé syndrome (BHD) and this study investigates how lung cysts in BHD differ from those in other cystic lung diseases.
- In a retrospective analysis of 52,823 patients, 301 were identified with multiple lung cysts, with 24 (8%) diagnosed with BHD; most BHD patients showed bilateral cysts and larger sizes compared to other conditions.
- The study established a predictive model with high sensitivity (95.83%) and specificity (81.22%) to identify BHD based on characteristics like cyst location, size, and diversity, aiding in the diagnosis of previously undetected cases.
Article Synopsis
- A 47-year-old woman with a history of drug-resistant epilepsy was admitted to the emergency department due to sudden shortness of breath and chest pain, revealing low oxygen levels and signs of pulmonary issues.
- Imaging tests showed cystic lung lesions consistent with lymphangioleiomyomatosis and a collapsed lung, which was treated with a chest tube.
- Further examinations identified skin and kidney tumors related to angiomyolipoma, confirmed through biopsy, and genetic testing led to a diagnosis that prompted treatment with everolimus and dexamethasone.
Quantifying Spatial Distribution of Ventilation Defects in Multiple Pulmonary Diseases With Hyperpolarized Xenon MRI.
J Magn Reson Imaging
October 2024
Center for Pulmonary Imaging Research, Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Article Synopsis
- The study focuses on assessing lung ventilation using hyperpolarized Xe MRI, comparing ventilation defect percentage (VDP) with defect distribution index (DDI) to measure how defects cluster spatially in various pulmonary diseases.
- It involves 421 subjects, including healthy controls and individuals with various obstructive and restrictive lung conditions, analyzed using a 3T MRI system.
- Results indicate that DDI is significantly higher in many pulmonary conditions compared to healthy controls, correlating well with VDP and pulmonary function tests, especially in obstructive disease groups.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!