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Pembrolizumab as an effective treatment for diffuse malignant peritoneal mesothelioma with long‑term survival: A case report and literature review.
Oncol Lett
April 2025
Department of Integrative Oncology, China-Japan Friendship Hospital, Beijing 100029, P.R. China.
Primary diffuse malignant peritoneal mesothelioma (MPEM) is a malignant disease without standard treatments recommended. Recently, immunotherapy has revolutionized the field of tumor therapy. According to current clinical evidence, advanced MPEM may gain potential clinical benefits from immune checkpoint inhibitors.
View Article and Find Full Text PDFCongenital neoplasms in cattle: A literature review and multi-institutional case series.
J Vet Diagn Invest
March 2025
Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible (IPADS, INTA Balcarce-CONICET), Balcarce, Argentina.
Congenital neoplasms are rare and sporadic in cattle and can cause losses due to abortions and perinatal or neonatal deaths. The etiopathogenesis of congenital tumors in bovine fetuses and neonates is largely unknown, and their diagnosis is often challenging. Here we review the literature on congenital tumors in cattle and report 11 additional cases diagnosed at veterinary diagnostic laboratories in Argentina, Uruguay, the United States, and the United Kingdom, namely 4 congenital lymphomas, 3 mesotheliomas, 2 adenomatoid tumors, 1 lymphangioma, and 1 ovarian sex cord-stromal tumor in bovine fetuses and/or neonatal calves.
View Article and Find Full Text PDFCardiac herniation identified without any symptoms following extrapleural pneumonectomy: a case report.
Gen Thorac Cardiovasc Surg Cases
March 2025
Division of Thoracic Surgery, Department of Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-Cho, Kamigyo-Ku, Kyoto, 602-8566, Japan.
Background: Cardiac herniation, especially right-sided herniation, is a fatal complication which causes sudden hypotension due to obstruction of the vena cava. Here, we describe a case of cardiac herniation identified without any symptoms after right extrapleural pneumonectomy performed for diffuse pleural mesothelioma.
Case Presentation: A 72-year-old man with diffuse pleural mesothelioma underwent a right extrapleural pneumonectomy after chemotherapy.
Miliary spread of mesothelioma is a rare but important manifestation of late-stage disease, likely due to hematogenous dissemination. This case highlights characteristic CT imaging findings, emphasizing the need for awareness among clinicians and radiologists. Recognizing this pattern can aid in diagnosis, prognostication, and appropriate referral for palliative management.
View Article and Find Full Text PDFSarcomatoid pleural mesothelioma evaluated using diffusion-weighted whole-body imaging with background body signal suppression.
Respir Investig
March 2025
Department of Respiratory Medicine, Kainan Hospital Aichi Prefectural Welfare Federation of Agricultural Cooperatives, Yatomi, Aichi, 498-8502, Japan.
An 83-year-old man with a history of asbestos exposure presented with dyspnea. Thoracic computed tomography showed right-sided pleural effusion and heterogeneous pleural thickening with calcified plaques. Thoracentesis revealed exudative fluid, and the cytology results were negative for malignancy.
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