Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3382/ps.0491728 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses.
Br J Psychiatry
January 2025
Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, USA; Department of Human Genetics, University of California Los Angeles, USA; and Department of Computational Medicine, University of California Los Angeles, USA.
Background: Accurate diagnosis of bipolar disorder (BPD) is difficult in clinical practice, with an average delay between symptom onset and diagnosis of about 7 years. A depressive episode often precedes the first manic episode, making it difficult to distinguish BPD from unipolar major depressive disorder (MDD).
Aims: We use genome-wide association analyses (GWAS) to identify differential genetic factors and to develop predictors based on polygenic risk scores (PRS) that may aid early differential diagnosis.
Genome-Wide Association Study and Genomic Predictions for Hydroxycinnamate Concentrations in Maize Stover.
J Agric Food Chem
January 2025
UA MBG-UVIGO, Misión Biológica de Galicia (CSIC), Pazo de Salcedo, Pontevedra 36143, España.
Hydroxycinnamates, like ferulate (FA) and -coumarate (CA), are important components of maize cell walls, which influence pest resistance, ruminal digestibility, and biofuel production. Increasing their concentration has been linked to increased pest resistance, but also may lead to a decrease in nutritional value or bioethanol production efficiency. Therefore, improving forage quality or biofuel production without compromising plant resistance and a thorough understanding of the biosynthesis and deposition of these compounds is necessary, especially in stover, which is the feedstock for second-generation biofuel production and determines animal forage quality.
View Article and Find Full Text PDFGenetic parameters and single-step genome-wide association analysis for trematode (Fasciola hepatica and Calicophoron/Paramphistomum spp.) infections in German dairy cows.
Infect Genet Evol
January 2025
Institute of Animal Breeding and Genetics, Justus-Liebig-University Gießen, 35390 Gießen, Germany.
Infections with the liver fluke (Fasciola hepatica) cause economic losses in cattle production worldwide. Also, infections with rumen flukes (Calicophoron/Paramphistomum spp.) are gaining importance in grazing cattle in Europe.
View Article and Find Full Text PDFHigh-Throughput Phenotyping for Agronomic Traits in Cassava Using Aerial Imaging.
Plants (Basel)
December 2024
Embrapa Mandioca e Fruticultura, Nugene, Cruz das Almas 44380-000, Bahia, Brazil.
Large-scale phenotyping using unmanned aerial vehicles (UAVs) has been considered an important tool for plant selection. This study aimed to estimate the correlations between agronomic data and vegetation indices (VIs) obtained at different flight heights and to select prediction models to evaluate the potential use of aerial imaging in cassava breeding programs. Various VIs were obtained and analyzed using mixed models to derive the best linear unbiased predictors, heritability parameters, and correlations with various agronomic traits.
View Article and Find Full Text PDFGenetic parameters for milk production traits of Simmental cows with random regression test-day model.
Animal
December 2024
National Research Institute of Animal Production, ul. Krakowska 1, 32-083 Balice, Poland.
Precise genetic parameter estimates can allow the breeding value evaluation to be adjusted to meet European requirements and to enable participation in the international evaluation of Simmental bulls conducted by Interbull. Genetic parameters were estimated for a multitrait multilactation random regression test-day model for milk in Simmental cattle in Poland. Data came from the official Polish national recording system.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!