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[Aberrant Expression of Small Nucleolar RNA and Its Clinical Significance in Patients with Acute Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2024
Department of Anatomy, School of Basic Medicine, Guangdong Medical University, Dongguan Key Laboratory of Experimental Animal Resources Development and Application Research of Biomedical Industry, Dongguan 523808, Guangdong Province, China.E-mail:
Objective: To investigate the expression level of small nucleolar RNA (snoRNA) in bone marrow of patients with acute leukemia (AL) and its significance in the clinical diagnosis, treatment and prognosis of AL patients.
Methods: Bone marrow samples of 53 newly diagnosed AL patients and 29 healthy subjects in the Affiliated Hospital of Guangdong Medical University from March 2018 to December 2021 were collected. Quantitative real-time polymerase chain reaction (qRT-PCR) was used to detect the relative expression level of in bone marrow mononuclear cells of the two groups.
[The Clinical Efficacy of Small Dose CAG Program in Comparison with MA Program in Senile Patients with Acute Myeloid Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2018
Department of hematology, Qilu Hospital, Shandong University, Jinan 250012, Shandong Province,
Objective: To compare the clinical efficacy of small dose CAG regimen and MA regimen in the senile patients with acute myeloid leukemia(AML).
Methods: The clinical data of 83 senile patients with AML from Sep. 2012 to Sep.
Reported case of leukemic retinopathy mimicking common ischemic retinopathies in a young adult where ophthalmic visit was the first step to the diagnosis of chronic myeloid leukemia. It highlights the importance of routine eye exams and that clinicians should suspect leukemia in an otherwise healthy patient presenting with ischemic retinopathy.
View Article and Find Full Text PDFMyeloid Sarcoma "en plaque" Disguised as Acute Subdural Hematoma.
Can J Neurol Sci
May 2016
1Division of Neurosurgery, McMaster University,Hamilton,Ontario,Canada.
[Safety of polyethylene glycol conjugated L-asparaginase in patients with acute lymphoblastic leukemia and T cell non-Hodgkin lymphoma].
Zhonghua Xue Ye Xue Za Zhi
March 2015
Department of Hematology, Chinese Academy of Medical Sciences Affiliated Peking Union Medical College Hospital, Beijing 100730, China.
Objective: To evaluate the safety of polyethylene glycol conjugated L-asparaginase (PEG-Asp) for patients with adult acute lymphoblastic leukemia (ALL) and T cell non-Hodgkin lymphoma (T-NHL).
Methods: A retrospective analysis was conducted on the clinical data of 101 young patients (≤40 years old) with ALL and T-NHL, diagnosed at Peking Union Medical College Hospital between January 2012 and June 2014.
Results: A total of 480 doses of PEG-Asp were administered in 44 cases with ALL and 57 patients with T-NHL.
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