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Free-Breathing Respiratory Triggered High-Pitch Lung CT: Insights From Phantom and Patient Scans.
Invest Radiol
January 2025
From the Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (A. Schwarz, A. Simon, A.M.); Siemens Healthineers AG, Forchheim, Germany (A. Schwarz, C.H., J.D., A. Simon); Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany (F.K.W., S.G., M.S.); and Institut for Radiology, Pediatric and Neuroradiology, Helios Hospital, Schwerin, Germany (H.-J.R.).
Objective: Respiratory motion can affect image quality and thus affect the diagnostic accuracy of CT images by masking or mimicking relevant lung pathologies. CT examinations are often performed during deep inspiration and breath-hold to achieve optimal image quality. However, this can be challenging for certain patient groups, such as children, the elderly, or sedated patients.
View Article and Find Full Text PDFA Series of 40 Congenital Lung Malformation Cases and the Informative Value of CPAM Lesion Ratios.
Pediatr Rep
January 2025
Clinic for Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Introduction: In this single-center retrospective analysis, we present case data and insights gathered over the past eight years. Additionally, we computed postnatal, pre-therapy lesion-to-lung ratios of Congenital Pulmonary Airway Malformations (CPAMs) to retrospectively assess potential outcome prediction using lesion-to-lung ratios.
Methods: Data were collected between 2015 and 2022.
Prevalence and characteristics of adults with preserved ratio impaired spirometry (PRISm): Data from the BOLD Australia study.
Chron Respir Dis
January 2025
The Woolcock Institute of Medical Research, The University of Sydney, Sydney, Australia.
Individuals with Preserved Ratio Impaired Spirometry (PRISm), defined as FEV/FVC ≥0.7 and FEV1 <80% predicted, are at higher risk of developing COPD. However, data for Australian adults are limited.
View Article and Find Full Text PDFDeep learning-based synthetic CT for dosimetric monitoring of combined conventional radiotherapy and lattice boost in large lung tumors.
Radiat Oncol
January 2025
Department of Radiotherapy, Changzhou Cancer Hospital, Honghe Road, Xinbei Area, Changzhou, 213032, China.
Purpose: Conventional radiotherapy (CRT) has limited local control and poses a high risk of severe toxicity in large lung tumors. This study aimed to develop an integrated treatment plan that combines CRT with lattice boost radiotherapy (LRT) and monitors its dosimetric characteristics.
Methods: This study employed cone-beam computed tomography from 115 lung cancer patients to develop a U-Net + + deep learning model for generating synthetic CT (sCT).
Validation of a Monte Carlo-based dose calculation engine including the 1.5 T magnetic field for independent dose-check in MRgRT.
Phys Med
January 2025
Department of Radiation Oncology, IRCCS Sacro Cuore Don Calabria Hospital, Via Don A. Sempreboni 5, 37024 Negrar di Valpolicella, VR, Italy; University of Brescia, Brescia, Italy.
Purpose: Adaptive MRgRT by 1.5 T MR-linac requires independent verification of the plan-of-the-day by the primary TPS (Monaco) (M). Here we validated a Monte Carlo-based dose-check including the magnetostatic field, SciMoCa (S).
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