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http://dx.doi.org/10.1042/bj1200433 | DOI Listing |
Mol Oncol
January 2025
Shanghai Stomatological Hospital & School of Stomatology & Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Colorectal cancer (CRC) is a prevalent malignant tumor worldwide, with a high mortality rate due to its complex etiology and limited early screening techniques. This study aimed to identify potential biomarkers for early detection of CRC utilizing targeted metabolite profiling of platelet-rich plasma (PRP). Based on multiple reaction monitoring (MRM) mode, liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis identified metabolites in PRP collected from patients with CRC (n = 70) and healthy controls (n = 30).
View Article and Find Full Text PDFSci Rep
December 2024
College of Biological Sciences and Technology, YiLi Normal University, Yining, 835000, People's Republic of China.
Ice wine is produced from concentrated grape juice obtained by the natural freezing and pressing of grapes. The high sugar content of this juice has an impact on fermentation. To investigate the impact of the initial sugar concentration on the fermentation of ice wine, the initial sugar concentration of Vidal ice grape juice was adjusted to 370, 450, 500 and 550 g/L by the addition of glucose.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Marine, Faculty of Fisheries and Marine, Universitas Airlangga, Campus C UNAIR, Mulyorejo, Surabaya 60115, Indonesia; Research Group of Post-harvest, Processing Technology, and Bioproducts, Faculty of Fisheries and Marine, Universitas Airlangga, Mulyorejo, Surabaya 60115, Indonesia. Electronic address:
Composite polymers are promising solution to structural setbacks of starch and alginate-based films due to their hydrophilic attributes. Hence, this study aimed to investigate young coconut jelly powder (CJP), an under-utilized by-waste, as a filler using the casting method to develop a novel biocomposite from increments of CJP (1-3 %) to a blended resin of arrowroot starch, sodium alginate, and glycerol. Moreover, the films were characterized by physicomechanical (visual aspect, thickness, color, moisture content, tensile strength, and elongation at break); surface microstructure; water barrier (water vapor permeability, water solubility, and water activities); thermal, crystallinity, and functional group properties; soil, river water, and seawater biodegradability; and coating application in cherry tomato.
View Article and Find Full Text PDFJ Funct Biomater
December 2024
BioMedical Systems Engineering Laboratory, Panoz Institute, School of Pharmacy and Pharmaceutical Sciences, Trinity College, D02 PN40 Dublin, Ireland.
Stem cells have been widely used to produce artificial bone grafts. Nonetheless, the variability in the degree of stem cell differentiation is an inherent drawback of artificial graft development and requires robust evaluation tools that can certify the quality of stem cell-based products and avoid source-tissue-related and patient-specific variability in outcomes. Omics analyses have been utilised for the evaluation of stem cell attributes in all stages of stem cell biomanufacturing.
View Article and Find Full Text PDFGels
November 2024
Department of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi 573-1121, Osaka, Japan.
Bone tissue engineering is a technique that simulates the bone tissue microenvironment by utilizing cells, tissue scaffolds, and growth factors. The collagen hydrogel is a three-dimensional network bionic material that has properties and structures comparable to those of the extracellular matrix (ECM), making it an ideal scaffold and drug delivery system for tissue engineering. The clinical applications of this material are restricted due to its low mechanical strength.
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