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PLoS Biol
January 2025
School of Biosciences and Bateson Centre, University of Sheffield, Western Bank, Sheffield, United Kingdom.
Heart development involves the complex structural remodelling of a linear heart tube into an asymmetrically looped and ballooned organ. Previous studies have associated regional expansion of extracellular matrix (ECM) space with tissue morphogenesis during development. We have developed morphoHeart, a 3D tissue segmentation and morphometry software with a user-friendly graphical interface (GUI) that delivers the first integrated 3D visualisation and multiparametric analysis of both heart and ECM morphology in live embryos.
View Article and Find Full Text PDFBJUI Compass
January 2025
Service d'Urologie, Andrologie, Transplantation Rénale, Hôpital Pasteur 2, CHU de Nice Nice France.
Objectives: The objective is to compare the learning curves between two pioneer and three second-generation surgeons for RAPN in terms of WIT, CD and positive surgical margins.
Materials And Methods: The charts of consecutive RAPNs of three centres were reviewed from the UroCCR prospective database. The experience was assessed by a regression model for each group.
MethodsX
June 2025
School of Social Sciences and Languages, Vellore Institute of Technology, Chennai, India.
Understanding the relationship between Learned Helplessness (LH) and Psychological Capital (PsyCap) is essential for developing effective interventions for Indigenous adolescents. This study explored the role of PsyCap as a mediator in the link between LH and Psychological Well-Being (PWB). Total of 173 Indigenous adolescents (85 boys and 88 girls) from sixth to eleventh grade at government residential schools.
View Article and Find Full Text PDFFront Chem
January 2025
Department of Mathematics and Statistics, Hazara University, Mansehra, Pakistan.
This study investigates the significance of single-walled (SWCNTs) and multi-walled (MWCNTs) carbon nanotubes with a convectional fluid (water) over a vertical cone under the influences of chemical reaction, magnetic field, thermal radiation and saturated porous media. The impact of heat sources is also examined. Based on the flow assumptions, the fundamental flow equations are modeled as partial differential equations (PDEs).
View Article and Find Full Text PDFBMC Bioinformatics
January 2025
Biology Department, University of Massachusetts Amherst, Amherst, MA, USA.
Background: High-throughput behavioral analysis is important for drug discovery, toxicological studies, and the modeling of neurological disorders such as autism and epilepsy. Zebrafish embryos and larvae are ideal for such applications because they are spawned in large clutches, develop rapidly, feature a relatively simple nervous system, and have orthologs to many human disease genes. However, existing software for video-based behavioral analysis can be incompatible with recordings that contain dynamic backgrounds or foreign objects, lack support for multiwell formats, require expensive hardware, and/or demand considerable programming expertise.
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