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Rutin: Family Farming Products' Extraction Sources, Industrial Applications and Current Trends in Biological Activity Protection.
Molecules
August 2023
Facultad de Ingeniería y Administración, Universidad Nacional de Colombia, Carrera. 32 Chapinero, Palmira 763533, Colombia.
In vitro and in vivo studies have demonstrated the bioactivity of rutin, a dietary flavonol naturally found in several plant species. Despite widespread knowledge of its numerous health benefits, such as anti-inflammatory, antidiabetic, hepatoprotective and cardiovascular effects, industrial use of rutin is still limited due to its low solubility in aqueous media, the characteristic bitter and astringent taste of phenolic compounds and its susceptibility to degradation during processing. To expand its applications and preserve its biological activity, novel encapsulation systems have been developed.
View Article and Find Full Text PDFImplementing machine learning to optimize the cost-benefit of urban water clarifier geometrics.
Water Res
July 2022
Engineering School of Sustainable Infrastructure and Environment, University of Florida, Gainesville, Florida 32611, USA.
Clarification basins are ubiquitous water treatment units applied across urban water systems. Diverse applications include stormwater systems, stabilization lagoons, equalization, storage and green infrastructure. Residence time (RT), surface overflow rate (SOR) and the Storm Water Management Model (SWMM) are readily implemented but are not formulated to optimize basin geometrics because transport dynamics remain unresolved.
View Article and Find Full Text PDFFine Particle Fraction: The Good and the Bad.
J Aerosol Med Pulm Drug Deliv
January 2022
Stephen P. Newman, 6 Nelson Drive, Hunstanton PE36 5DU, United Kingdon of Great Britain and Northern Ireland.
Fine particle fraction (FPF) is defined in general terms as the fraction or percentage of the drug mass contained in an aerosol cloud that may be small enough to enter the lungs and exert a clinical effect. An aerodynamic diameter of 5 μm represents the approximate border between "fine" and "coarse" particles, but there is no universally agreed upon definition of FPF in terms of an aerodynamic particle size range. FPF alone does not adequately describe a heterodisperse aerodynamic particle size distribution, and it needs to be combined with another measure or measures indicating the width of the distribution.
View Article and Find Full Text PDFCFD and physical models of PM separation for urban drainage hydrodynamic unit operations.
Water Res
May 2019
Engineering School of Sustainable Infrastructure and Environment, U. of Florida, Gainesville, FL, 32611, United States. Electronic address:
A hydrodynamic separator (HS) is a common pre-treatment unit operation (UO) for separating coarser particulate matter (PM). While HS designs have disparate internal geometries, surface areas, and volumes; for a given PM granulometry this study hypothesizes there are limits to PM separation. In this study, a large group of full-scale HS units were tested with physical and computational fluid dynamics (CFD) models to evaluate HS functionality based on surface overflow rate (SOR), HS geometrics (diameter, height, baffling), PM granulometry, particle size distribution (PSD), turnover volume, hydraulic capacity, and short-circuiting.
View Article and Find Full Text PDFExperimental Evaluation of Perfluorocarbon Aerosol Generation with Two Novel Nebulizer Prototypes.
Pharmaceutics
January 2019
Department of Nautical Science and Marine Systems, University of the Basque Country UPV/EHU, 48013 Portugalete, Bizkaia, Spain.
The potential of non-invasive ventilation procedures and new minimally invasive techniques has resulted in the research of alternative approaches as the aerosolization for the treatment of respiratory distress syndrome (RDS). The aim of this work was to design two nebulizer prototypes and to evaluate them studying the particle size distribution of the inhaled droplets generated with distilled water and two perfluorocarbons (PFCs). Different experiments were performed with driving pressures of 1⁻3 bar for each compound.
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