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GARRE'S OSTEOMYELITIS OF LONG BONE IN ADULT.
J Ayub Med Coll Abbottabad
December 2024
Department of Orthopaedic, Ayub Medical College, Abbottabad-Pakistan.
Garre's osteomyelitis is a rare form of chronic osteomyelitis characterized by sclerosing and periosteal reaction of the affected bone. We report a case of a 35-year-old woman who presented with left tibial pain and swelling for 18 months. She was diagnosed with Garre's osteomyelitis of the mid-shaft tibia based on radiological and histopathological findings.
View Article and Find Full Text PDFHyperphosphatemic Familial Tumoral Calcinosis.
South Med J
December 2024
Department of Dermatology, Mayo Clinic, Jacksonville, Florida.
Hyperphosphatemic familial tumoral calcinosis (HFTC) is a rare, autosomal recessive condition characterized by fibroblast growth factor 23 signaling pathway dysregulation, hyperphosphatemia and ectopic calcifications (which manifest as joint motion limitations), inflammatory bony pain, and disability. Given the rarity and multiorgan involvement of HFTC, a multidisciplinary approach including Dermatology, Ophthalmology, Dentistry, Nephrology, Endocrinology, Rheumatology, and Genetics is necessary for diagnosis and treatment. We present a multidisciplinary diagnostic and treatment approach for a patient with HFTC due to a gene mutation with unique imaging highlighting the extent of calcinosis seen in HFTC.
View Article and Find Full Text PDFBiomechanical Analysis of Diffuse Idiopathic Skeletal Hyperostosis and Osteoporosis: Vertebral Fracture Risk Evaluation Using Finite Element Modeling with Clinical and Micro-CT Data in an Elderly Donor.
Biomedicines
October 2024
Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, 18057 Rostock, Germany.
Biomechanical analysis of spinal structures is crucial in the evaluation of injuries, the risk of fracture, and age-related changes. Osteoporotic vertebrae are very fragile and therefore constitute a serious risk, especially in the elderly. At present, clinically relevant decision making in fracture risk assessment is predicated upon finite element analysis (FEA), which utilizes high-resolution computed tomography (CT) scans from clinical practice alongside micro-CT scans from laboratory settings.
View Article and Find Full Text PDFCaffey disease in an infant.
BMJ Case Rep
November 2024
Paediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
A previously healthy female infant was brought to the paediatrics outpatient department by her mother reporting increased irritability and swelling behind her left shoulder, accompanied by restricted movement in her left arm. The irritability had been present for the past 5 months, with swelling also noticed at that time, gradually increasing in size. On examination, a large, firm, immobile mass was detected on the left scapular region.
View Article and Find Full Text PDFCase Report: A male newborn with occipital horn syndrome.
F1000Res
November 2024
Neonatal Intensive Care Unit, King Fahad Medical City, Riyadh, Saudi Arabia.
Article Synopsis
- - Occipital horn syndrome (OHS) is a rare genetic disease linked to a defective ATP7A gene, affecting the copper transport system and primarily impacting musculoskeletal and connective tissues.
- - A male neonate diagnosed with OHS showed distinctive symptoms such as occipital exostosis, skin laxity at the nape, and widely opened skull sutures shortly after birth.
- - This case is significant as it stresses the need for thorough investigation of early symptoms and demonstrates the essential role of early diagnosis and collaborative care in improving outcomes for patients with OHS.
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