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Background: Our previous preclinical study demonstrated that -targeted replacement mice exhibit more severe cerebral hypoperfusion and cognitive impairment than -targeted replacement mice with carotid artery stenosis due to neurovascular dysfunction. Therefore, we clinically investigate whether contributes to cerebral hemodynamic and cognitive impairment in subjects with asymptomatic carotid artery stenosis or occlusion.
Methods And Results: A cross-sectional observational study was conducted between January 2017 and March 2022.
A longitudinal study on the effect of aerobic exercise intervention on the inhibitory control in college students with internet addiction.
Front Hum Neurosci
February 2025
School of Sports Science, Jishou University, Jishou, Hunan, China.
Objectives: This study aimed to investigate the effects of aerobic exercise on reactive inhibitory control in college students with internet addiction, examining both behavioral and electrophysiological changes over time.
Methods: A longitudinal study design was adopted, involving 48 male college students with internet addiction who were randomly assigned to either a control group or an experimental group. Participants in the experimental group engaged in 40 min aerobic cycling sessions three times per week for 12 weeks, while the control group maintained their usual physical activity levels without any intervention.
Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
Nutrients
February 2025
Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands.
: Post-menopausal women are at an increased risk of developing cardiovascular disease. Menaquinone-7 (MK-7) is a fat-soluble vitamin involved in coagulation and maintaining vascular health. The aim of the post hoc analysis of this one-year study is to investigate the effects of MK-7 supplementation on the vascular parameters in pre-, peri-, and post-menopausal women.
View Article and Find Full Text PDFBody Mass Index and Cardiovascular Risk Markers: A Large Population Analysis.
Nutrients
February 2025
Boston Heart Diagnostics, 200 Crossing Blvd, Suite 200, Framingham, MA 01702, USA.
An elevated body mass index (BMI) has been added to the new American Heart Association atherosclerotic cardiovascular disease (ASCVD) risk model. Our goal in this study was to examine the relationships between BMI and traditional and non-traditional ASCVD risk factors. We measured levels of blood glucose, insulin, lipids, lipoproteins, sterols, fatty acids, markers of inflammation and oxidative stress, and hormones in 226,000 middle-aged and elderly subjects (55% women) and associated those parameters to BMI in 5 groups (BMI 20-25, 25.
View Article and Find Full Text PDFState-of-the-Art Review of the Performance of Fiber-Reinforced-Composite-Confined Concrete Columns at Ambient Temperatures.
Materials (Basel)
March 2025
The Southern Scientific Center of the Russia Academy of Sciences, Moscow 4119049, Russia.
This paper investigates the effect of fiber-reinforced composites (FRPs) on the mechanical properties of concrete under ambient conditions. It begins with an examination of the various types of FRP and their advantages, followed by a review of isostructural models for passively restrained concrete under ambient conditions. These models are categorized into two main groups: those assuming constant confining stresses and those that incorporate stress constraints related to the loading history.
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