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Inaudible airborne ultrasound affects emotional states in the olfactory bulbectomized rat depression model.
Sci Rep
January 2025
Laboratory of Pharmacology, Department of Pharmacy, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Recently, exposure to sounds with ultrasound (US) components has been shown to modulate brain activity. However, the effects of US on emotional states remain poorly understood. We previously demonstrated that the olfactory bulbectomized (OBX) rat depression model is suitable for examining the effects of audible sounds on emotionality.
View Article and Find Full Text PDFThe oxygen level in air directs airway epithelial cell differentiation by controlling mitochondrial citrate export.
Sci Adv
January 2025
Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Oxygen controls most metazoan metabolism, yet in mammals, tissue O levels vary widely. While extensive research has explored cellular responses to hypoxia, understanding how cells respond to physiologically high O levels remains uncertain. To address this problem, we investigated respiratory epithelia as their contact with air exposes them to some of the highest O levels in the body.
View Article and Find Full Text PDFMOX Nanosensors to Detect Colorectal Cancer Relapses from Patient's Blood at Three Years Follow-Up, and Gender Correlation.
Biosensors (Basel)
January 2025
Department of Neuroscience and Rehabilitation, University of Ferrara, 44121 Ferrara, Italy.
Colorectal cancer represents 10% of all the annual tumors diagnosed worldwide, being often not timely diagnosed, because its symptoms are typically lacking or very mild. Therefore, it is crucial to develop and validate innovative low-invasive techniques to detect it before becoming intractable. To this aim, a device equipped with nanostructured gas sensors has been employed to detect the airborne molecules of blood samples collected from healthy subjects, and from colorectal cancer affected patients at different stages of their pre- and post-surgery therapeutic path.
View Article and Find Full Text PDFExposomic Determinants of Atherosclerosis: Recent Evidence.
Curr Atheroscler Rep
January 2025
Houston Methodist DeBakey Heart and Vascular Center, Houston, TX, USA.
Purpose Of Review: The exposome refers to the total environmental exposures a person encounters throughout life, and its relationship with human health is increasingly studied. This non-systematic review focuses on recent research investigating the effects of environmental factors-such as air pollution, noise, greenspace, neighborhood walkability, and metallic pollutants-on atherosclerosis, a major cause of cardiovascular disease.
Recent Findings: Studies show that long-term exposure to airborne particulate matter can impair endothelial function and elevate adhesion molecule levels, leading to vascular damage.
Airborne Escherichia coli bacteria biosynthesize lipids in response to aerosolization stress.
Sci Rep
January 2025
Aerosol Technology Laboratory, Biological and Agricultural Engineering Department, Texas A&M University, College Station, TX, 77843, USA.
Gram-negative bacteria pose an increased threat to public health because of their ability to evade the effects of many antimicrobials with growing antibiotic resistance globally. One key component of gram-negative bacteria resistance is the functionality and the cells' ability to repair the outer membrane (OM) which acts as a barrier for the cell to the external environment. The biosynthesis of lipids, particularly lipopolysaccharides, or lipooligosaccharides (LPS/LOS) is essential for OM repair.
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