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Endometriosis is a chronic disease characterised by the presence of endometrial tissue outside the uterine cavity, affecting 5-15% of women, especially those of reproductive age. The disease may manifest itself as dysmenorrhoea, dyspareunia, sterility and chronic pelvic pain, among other symptoms. Although it is not malignant, it shares some characteristics with cancer and can lead to epithelial ovarian carcinoma.
View Article and Find Full Text PDFFlorid cystic endosalpingiosis: Diagnostic challenges and management in the spectrum of müllerian anomalies - A case report.
Int J Surg Case Rep
January 2025
Department of Gynecology and Obstetrics, Fatouma Bourguiba University Hospital, Tunisia.
Introduction And Importance: Cystic endosalpingiosis is a rare, benign condition characterized by the presence of fallopian tube-like epithelium outside the fallopian tubes. It predominantly affects menopausal women and is often asymptomatic. Florid cystic endosalpingiosis, an unusual form, can mimic malignant ovarian masses, making accurate diagnosis crucial.
View Article and Find Full Text PDFTailgut Cyst-Gynecologist's Pitfall: Literature Review and Case Report.
Diagnostics (Basel)
January 2025
2nd Department of Obstetrics and Gynecology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Retrorectal cystic hamartomas ("Tailgut cysts") are rare developmental cysts that appear in the retrorectal space, arising from aberrant remnants of the post-anal primitive gut in case of an incomplete embryogenetic involution. We present the case of a 30-year-old woman with a history of chronic lower abdominal pain. Other digestive symptoms, like rectal fullness, constipation, pain on defecation, rectal bleeding or genitourinary obstruction symptoms, were not associated.
View Article and Find Full Text PDFNipecotic Acid Ameliorates Letrozole Induced Poly Cystic Ovarian Syndrome in Female Virgin Wistar Rats by Modulating Hypothalamic-Pituitary-Gonadal (HPG) Axis Regulated by GABA.
Reprod Sci
January 2025
Era College of Pharmacy, Era University, Lucknow, Uttar Pradesh, India.
PCOS is a common endocrine disorder in women particularly in their reproductive age. GABA has been implicated in the pathogenesis of PCOS through its central role in the hypothalamus. Hence, in this study we investigated the effect of Nipecotic acid (NPA) in Letrozole induced PCOS in female Wistar rats as NPA has been proven as a GABA uptake inhibitor.
View Article and Find Full Text PDFValue of MRI-Based Ovarian-Adnexal Reporting and Data System for the Diagnosis of Adnexal Masses.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
December 2024
Department of Radiology,The Central Hospital of Wuhan,Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430014,China.
Objective To assess the value of the MRI-based ovarian-adnexal reporting and data system (O-RADS MRI) for the diagnosis of adnexal masses. Methods A total of 407 patients who underwent dynamic contrast enhancement (DCE)-MRI and pathological examination (gold standard) at the Department of Radiology,Central Hospital of Wuhan between May 2017 and December 2022 were enrolled in this study.Two radiologists performed the O-RADS MRI scoring of adnexal masses according to MRI features and calculated the malignancy rate of adnexal masses by O-RADS MRI score,enhancement type,and mass type.
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