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Introduction: Early pregnancy care involves the screening and identification of women with risk factors for adverse pregnancy outcomes, including stillbirth or preterm birth, to tailor pregnancy care and interventions accordingly. Most stillbirths and approximately two-thirds of preterm births, however, occur in the absence of evident risk factors. The majority of stillbirths occur in the preterm period, yet there are few interventions targeting this period, and progress to reduce stillbirth rates remains slow.
View Article and Find Full Text PDFPerinatal outcomes and predictors of placental abruption: a retrospective study in an Ethiopian tertiary care center.
Front Public Health
January 2025
Department of Epidemiology, St. Peter Specialized Hospital, Addis Ababa, Ethiopia.
Background: Placental abruption is a critical obstetric condition characterized by the premature separation of the placenta from the uterus, leading to severe maternal and fetal complications. In Ethiopia, the maternal and perinatal morbidity and mortality rates are alarmingly high, and placental abruption significantly contributes to these adverse outcomes. Despite its severity, there is a lack of comprehensive data on the burden, risk factors, and outcomes associated with placental abruption in the Ethiopian context.
View Article and Find Full Text PDFHigh performance of the diffusion magnetic resonance imaging biomarker diffusion-derived 'vessel density' (DDVD) for separating placentas associated with pre-eclampsia from placentas in normal pregnancy.
Quant Imaging Med Surg
January 2025
Department of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
Background: Diffusion-derived 'vessel density' (DDVD) is a surrogate of the area of micro-vessels per unit tissue. DDVD is calculated according to: DDVD (b0b50) = Sb0/ROIarea0 - Sb50/ROIarea50, where Sb0 and Sb50 refer to the tissue signal when is 0 or 50 s/mm. Due to the complexity of pre-eclampsia (PE), even a combination of risk factors and available tests cannot accurately diagnose or predict PE.
View Article and Find Full Text PDFNeonatal cost savings in hypertensive disorders of pregnancy: Economic evaluation of the sFlt-1/PlGF test with real world implementation of biomarkers.
Pregnancy Hypertens
January 2025
Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology, University of Chicago Medical Center, Chicago, IL, USA. Electronic address:
Background: Preeclampsia is a key cause of prematurity in the U.S. and incurs significant healthcare costs.
View Article and Find Full Text PDFPregnancy, delivery, and neonatal outcomes among women with beta-thalassemia major: a population-based study of a large US database.
Arch Gynecol Obstet
January 2025
Department of Obstetrics & Gynecology, University of Tabuk, Tabuk, Saudi Arabia.
Purpose: We explored the effect of beta-thalassemia major on pregnancy and delivery outcomes in non-endemic area, utilizing USA population database.
Methods: This is a retrospective study utilizing data from the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample. A cohort of all deliveries between 2011 and 2014 was created using ICD-9 codes.
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