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A model of care redesign within rheumatology: A mixed methods approach integrating nurse practitioners and physician assistants.
J Am Assoc Nurse Pract
January 2025
Division of Cardiology, Department of Medicine, Duke Health Integrated Practice, Duke University Health System, Durham, North Carolina.
Background: Increasing patient demand and clinician burnout in rheumatology practices have highlighted the need for more efficient models of care (MOC). Interprofessional collaboration is essential for improving patient outcomes and clinician satisfaction.
Local Problem: Our current MOC lacks standardization and formal integration of Nurse Practitioners (NPs) and Physician Assistants (PAs), resulting in reduced clinician satisfaction and limited patient access.
Targeted inhibition of PqsR in Pseudomonas aeruginosa PAO1 quorum-sensing network by chalcones as promising antibacterial compounds.
Mol Biol Rep
January 2025
Department of Pharmaceutical Control, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Background: Pseudomonas aeruginosa's inherent and adapted resistance makes this pathogen a serious problem for antimicrobial treatments. Furthermore, its biofilm formation ability is the most critical armor against antimicrobial therapy, and the virulence factors, on the other hand, contribute to fatal infection and other recalcitrant phenotypic characteristics. These capabilities are harmonized through cell-cell communication called Quorum Sensing (QS), which results in gene expression regulation via three major interconnected circuits: las, rhl, and pqs system.
View Article and Find Full Text PDFNot getting better but not getting worse: A cluster randomized controlled pilot trial of a leadership implementation strategy.
Implement Res Pract
January 2025
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Background: Implementation of evidence-based practices (EBPs) in schools is fraught with challenges. Even when EBPs are initiated, deterioration of implementation efforts often hinders their long-term success. School leadership behaviors can influence teachers' EBP implementation.
View Article and Find Full Text PDFDifferential Associations of Intrapersonal and Interpersonal Emotion Regulation with Generalized Anxiety and Social Withdrawal Among Children.
J Genet Psychol
January 2025
Department of Educational Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
Anxiety and social withdrawal are common internalizing problems among children linked to poor emotion regulation (ER). We investigated how specific components of ER (emotion awareness, emotion regulation strategy) are associated with generalized anxiety and social withdrawal in the two ER domains (intrapersonal and interpersonal). Study participants were 398 fourth- and fifth-grade students (49% girls) and 22 teachers from a Midwestern state in the United States.
View Article and Find Full Text PDFRevolutionizing load harmony in edge computing networks with probabilistic cellular automata and Markov decision processes.
Sci Rep
January 2025
Cardiff School of Technologies, Cardiff Metropolitan University, Cardiff, UK.
In general, edge computing networks are based on a distributed computing environment and hence, present some difficulties to obtain an appropriate load balancing, especially under dynamic workload and limited resources. The conventional approaches of Load balancing like Round-Robin and Threshold-based load balancing fails in scalability and flexibility issues when applied to highly variable edge environments. To solve the problem of how to achieve steady-state load balance and provide dynamic adaption to edge networks, this paper proposes a new framework that using PCA and MDP.
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