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Rehabilitation - definition for research purposes.
Ann Agric Environ Med
December 2024
Department of Physical and Rehabilitation Medicine, Medical University of Lodz, Poland.
Introduction And Objective: The Rehabilitation Definition for Research Purposes (RDRP), published in 2022 by Cochrane Rehabilitation, addresses discrepancies resulting from the multiplicity and heterogeneity of rehabilitation definitions hitherto used in the contexts of science, health, and social/legal aspects. The RDRP, based on the paradigm of the International Classification of Functioning, Disability, and Health, provides clear-cut criteria for what rehabilitation includes and excludes. The final version of the RDRP achieved brad agreement among global stakeholders.
View Article and Find Full Text PDF[Clinical analysis of Tolosa-Hunt syndrome].
Zhonghua Yan Ke Za Zhi
January 2025
Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin300052, China.
Article Synopsis
- The study analyzed clinical features of Tolosa-Hunt syndrome (THS), a type of painful ophthalmoplegia, by collecting data from patients diagnosed at a hospital over four years.
- A total of 35 patients were included, with 18 diagnosed with THS, who typically presented symptoms like pain, ptosis, and MRI abnormalities, alongside various immunological findings.
- Treated with glucocorticoids, most THS patients saw symptom relief within weeks, though some experienced relapses during follow-up.
Analysis of complete genomes of Mycobacterium tuberculosis sublineage 2.1 (Proto-Beijing) revealed the presence of three pe_pgrs3-pe_pgrs4-like genes.
Sci Rep
December 2024
Pornchai Matangkasombut Center for Microbial Genomics, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok, 10400, Thailand.
Mycobacterium tuberculosis Complex (MTBC), the etiological agent of tuberculosis (TB), demonstrates considerable genotypic diversity with distinct geographic distributions and variable virulence profiles. The pe-ppe gene family is especially noteworthy for its extensive variability and roles in host immune response modulation and virulence enhancement. We sequenced an Mtb genotype L2.
View Article and Find Full Text PDFWhich fluoroquinolone is safer when combined with bedaquiline for tuberculosis treatment: evidence from FDA Adverse Event Reporting System database from 2013 to 2024.
Front Pharmacol
December 2024
Department of Infectious Disease, Shaoyang Central Hospital, Shaoyang, China.
Objective: To investigate which fluoroquinolone is safer when combined with bedaquiline for tuberculosis treatment by using the FDA Adverse Event Reporting System (FAERS) database.
Methods: We selected data from the first quarter (Q1) of 2013 to the second quarter (Q4) of 2024 from the FDA FAERS database for disproportionality analysis. Signal detection was conducted using the Reporting Odds Ratio (ROR), Proportional Reporting Ratio (PRR), Bayesian Confidence Propagation Neural Network (BCPNN), and Empirical Bayesian Geometric Mean (EBGM).
"Enriching the Hospital's Scientific Fame": Research at the Vienna Foundling Hospital.
Neonatology
December 2024
Background: Little is known about medical research at the Vienna Foundling Hospital during the 18th and 19th centuries.
Summary: The present paper focuses on nutrition, medical care, and research concerning newborn infants. In 1784, Emperor Joseph II merged obstetric and foundling hospitals under common leadership with specific statutes.
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