The authors describe a case of chronic endocarditis by Q fever, in a patient who had been operated for coarctation of the aorta twelve years previously and at the same time was carrier of a congenital bivalve aorta. The clinical picture was suggestive of subacute endocarditis, but the blood culture was negative repeatedly. There was also a prolonged and relapsing febrile syndrome over a period of one-year-and-a-half. The following data are also worthy of note: the coexistence of a liver disorder and a focal and segmentary glomerulonephritis. Based on some recent publications (one by the same group) the authors feel that Coxiellosis burnetti must be more frequent in their environment than is suspected.
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J Clin Med
November 2024
Department VI Cardiology-Cardiovascular Surgery, "Victor Babes" University of Medicine and Pharmacy of Timișoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.
: Thoracic aortic aneurysms (TAAs) are potentially life-threatening medical conditions, and their etiology involves both genetic and multiple risk factors. endocarditis is one of the most frequent causes of blood culture-negative infective endocarditis (BCNIE) in patients with previous cardiac surgery. Our review aims to emphasize the importance of genetic testing in patients with thoracic aortic aneurysms but also the importance of additional testing in patients with suspected endocarditis whose blood cultures remain negative.
View Article and Find Full Text PDFJ Infect Public Health
January 2025
National Reference Laboratory for Plague, Tularemia and Q fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, Kabudar Ahang, Hamadan, Iran; Department of Epidemiology and Biostatics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran. Electronic address:
Eur Heart J Case Rep
December 2024
Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Clin Case Rep
December 2024
Internal Medicine Department, Facultad de Medicina, Health Research Institute of the Balearic Islands (IdISBa) Hospital Universitario Son Espases, Universitat de Ses Illes Balears Palma Illes Balears Spain.
Diagnosis of Q fever endocarditis is challenging since clinical findings are non-specific and diagnosis is mainly made by indirect methods such as serology. A progressive constitutional syndrome, severe asthenia, anorexia with no fever and histopathological findings of non-necrotizing gastric granulomas in a gastric biopsy were found preceding a cardiac failure in our case report. Prolonged treatment with doxycycline and hydroxychloroquine is mandatory, and cardiac valve surgery may be needed.
View Article and Find Full Text PDFPerfusion
November 2024
Department of Cardiac Surgery, Southampton General Hospital, Southampton, UK.
Q-Fever is a rare condition with an often insidious presentation. Endocarditis is a serious complication of up to 5% of Q-Fever cases, with a higher incidence and mortality in patients with prosthetic valves. A 67-year-old man presented with a 6-weeks history of breathlessness on a background of previous bioprosthetic aortic valve replacement in 2018.
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