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Ascorbyl palmitate (ASC16) as a potential inhibitor of toxicity induced by Crotalus durissus terrificus venom.
Comp Biochem Physiol C Toxicol Pharmacol
October 2024
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Química Básica y Aplicada del Nordeste Argentino (IQUIBA-NEA), W3404AAS Corrientes, Argentina; Facultad de Ciencias Exactas y Naturales y Agrimensura, Universidad Nacional del Nordeste, W3404AAS Corrientes, Argentina. Electronic address:
It is well known that C. d. terrificus venom causes pathophysiological effects such as neuropathies, coagulopathies, and even death.
View Article and Find Full Text PDFExperimental production and efficacy testing of mono-specific antibodies against the venom of carpet viper (Echis ocellatus) from savannah Nigeria.
Toxicon
September 2024
College of Health Sciences, Bayero University Kano, Nigeria.
Echis ocellatus is one of the commonest snakes responsible for envenomation in Nigeria. Antivenom is the only effective treatment, but the country suffers from a limited supply of effective antivenom. This study therefore aimed to explore the feasibility of effective, mono-specific antibodies production through immunization in rabbits using the venom of Echis ocellatus from Nigeria.
View Article and Find Full Text PDFDevelopment and Efficacy of the Antivenom Specific to Severe Envenomations in Morocco and North Africa: Advancements in Scorpion Envenomation Management.
Toxins (Basel)
May 2024
Laboratory of Venoms and Toxins, Pasteur Institute of Morocco, 1 Place Louis Pasteur, Casablanca 20250, Morocco.
Scorpion envenomation poses a global public health issue, with an estimated 1,500,000 cases worldwide annually resulting in 2600 deaths. North Africa, particularly Morocco, experiences severe envenomations, mainly attributed to and in Morocco, and and in Algeria and Tunisia, with case numbers often underestimated. Current treatment relies mainly on symptomatic approaches, except in Morocco, where management is limited to symptomatic treatment due to controversies regarding specific treatment.
View Article and Find Full Text PDFExpression of Recombinant Stonustoxin Alpha Subunit and Preparation of polyclonal antiserum for Stonustoxin Neutralization Studies.
Protein J
June 2024
Department of Biology, Faculty of Basic Sciences, Imam Hossein University, Tehran, Iran.
Stonustoxin (SNTX) is a lethal protein found in stonefish venom, responsible for many of the symptoms associated with stonefish envenomation. To counter stonefish venom challenges, antivenom is a well-established and effective solution. In this study, we aimed to produce the recombinant alpha subunit protein of Stonustoxin from Synanceia horrida and prepare antibodies against it The SNTXα gene sequence was optimized for E.
View Article and Find Full Text PDFIsolation and characterization of novel Staphylococcus aureus bacteriophage Hesat from dairy origin.
Appl Microbiol Biotechnol
April 2024
Department of Biology, University of Pisa, Via San Zeno 37, 56127, Pisa, Italy.
A novel temperate phage, named Hesat, was isolated by the incubation of a dairy strain of Staphylococcus aureus belonging to spa-type t127 with either bovine or ovine milk. Hesat represents a new species of temperate phage within the Phietavirus genus of the Azeredovirinae subfamily. Its genome has a length of 43,129 bp and a GC content of 35.
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