The fibrinopeptides A and B of the gibbon (an Asian ape) have been characterized and their relation to other primate types examined. An allelic situation was discovered at location B-3; two of the gibbons studied had both glycine and serine at that position, whereas four others were homozygous for glycine.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1126/science.170.3956.468 | DOI Listing |
Br J Haematol
April 1996
Molecular Pathology Laboratory, Christchurch Hospital, New Zealand.
A patient referred for preoperative investigation of prolonged bleeding and easy bruising was found to have increased thrombin and reptilase times; however, the thrombin catalysed release of fibrinopeptides A and B was normal. Analysis of five other family members, spanning three generations, indicated that three had a similar defect and suggested autosomal dominant inheritance. Non-reducing SDS-PAGE of purified fibrinogen from affected individuals showed that the 340 kD form of their fibrinogen ran as a doublet.
View Article and Find Full Text PDFThe fibrinopeptides A and B of the gibbon (an Asian ape) have been characterized and their relation to other primate types examined. An allelic situation was discovered at location B-3; two of the gibbons studied had both glycine and serine at that position, whereas four others were homozygous for glycine.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!