Osteomyelitis and plasmacytoma.

N Engl J Med

Published: October 1970

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Solitary plasmacytomas (SPs) are tumors characterized by local monoclonal plasma cell proliferation, presenting without systemic manifestations. It mainly affects the axial skeleton, with calcaneal involvement being extremely rare. We report a case of a 48-year-old patient with a history of gunshot injury to his foot who presented with worsening heel pain and a calcaneal cyst.

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Article Synopsis
  • - Plasmacytoma is a rare condition involving plasma cell growth in bones or soft tissues, with types including solitary bone and extramedullary plasmacytomas; it can occur alongside chronic conditions like osteomyelitis.
  • - A 47-year-old man with a history of chronic osteomyelitis experienced ulceration in his tibia, leading to imaging tests that revealed dead bone and inflammation, prompting surgical intervention.
  • - Post-surgery, the diagnosis was confirmed as plasmacytoma, and the patient received successful radiotherapy; this case emphasizes the need for careful monitoring of chronic osteomyelitis for possible plasmacytoma development.
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