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Synchronous Acute Appendicitis and Cholecystitis.

CRSLS

January 2025

Department of Surgery, King Saud University Medical City, Riyadh, Saudi Arabia. (Drs. Aljunaydil, Mattar, Almufawaz, AlOthman, and Alalem).

Article Synopsis
  • Acute appendicitis and acute cholecystitis often occur together, and surgical management is effective for both conditions when they present simultaneously.
  • A 30-year-old female patient presented with abdominal pain and underwent imaging that confirmed the diagnoses, leading to a successful surgical intervention combining cholecystectomy and appendectomy.
  • The case underscores the importance of recognizing the possibility of both conditions occurring together and utilizing established management guidelines for effective treatment.
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Introduction: Untreated periodontitis significantly increases the risk of tooth loss, often delaying treatment due to asymptomatic phases. Recent studies have increasingly associated poor dental health with conditions such as rheumatoid arthritis, diabetes, obesity, pneumonia, cardiovascular disease, and renal illness. Despite these connections, limited research has investigated the relationship between appendicitis and periodontal disease.

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Detailed anamnesis and systematic physical examination are often relevant in the diagnostic routine of acute appendicitis. However, physicians are increasingly motivated to obtain radiological approval. Inherent limitations due to radiologists' experience and the presenting anatomy may result in contradictory outcomes between the described and intraoperative findings.

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Genomic insights of the emerging human pathogen sp. nov.

Heliyon

September 2024

Department of Gastroenterology and Hepatology, Shenzhen University General Hospital, Shenzhen University, Shenzhen, 518055, China.

Article Synopsis
  • The study investigates a newly identified species of opportunistic human pathogens associated with appendicitis, focusing on its genomic features and potential to cause infections.
  • Genomic comparisons were made using various bioinformatics tools to understand the similarities and differences between this species and closely related strains, revealing high average nucleotide identity and shared antimicrobial resistance genes.
  • The research highlights the evolutionary relationships and infection mechanisms of this emerging pathogen, providing valuable insights for developing targeted therapies.
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Appendiceal signet ring cell carcinoma is an exceedingly rare neoplasm which makes up only 4% of carcinomas of the appendix. It is a rare cause of abdominal pain which can mimic acute appendicitis. This case reports a 77-year-old female who presented to the emergency room with a complaint of right lower quadrant abdominal pain.

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