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Hepato-pancreato-biliary tuberculosis: A review.
Turk J Surg
June 2024
Department of Hepato-Pancreato Biliary Surgery and Liver Transplant, Mahatma Gandhi University of Medical Sciences, Jaipur, India.
Hepato-pancreato-biliary (HPB) tuberculosis (TB) is a rare form of extra-pulmonary TB that poses a diagnostic dilemma and is a great masquerader of malignancy. It is almost always curable but requires a high degree of suspicion and corroboratory evidence to document its existence. Medline/PubMed was searched with keywords "hepatic", "liver", "biliary" and "pancreatic" with "tuberculosis".
View Article and Find Full Text PDFAdministration of Alistipes indistinctus prevented the progression from nonalcoholic fatty liver disease to nonalcoholic steatohepatitis by enhancing the gut barrier and increasing Lactobacillus spp.
Biochem Biophys Res Commun
December 2024
School of Life Sciences and Medicine, Shandong University of Technology, Zibo, Shandong, 255000, People's Republic of China. Electronic address:
Metabolic-associated fatty liver disease (MAFLD) is an important public health problem, and the gut microbiota has become a new treatment target for MAFLD. Previously, A. indistinctus, a core gut bacterium, was shown to potentially contribute to the prevention of MAFLD.
View Article and Find Full Text PDFYellow tea polysaccharides protect against non-alcoholic fatty liver disease via regulation of gut microbiota and bile acid metabolism in mice.
Phytomedicine
October 2024
School of Life Sciences, Anhui University, Hefei, Anhui 230601, PR China; Key Laboratory for Ecological Engineering and Biotechnology of Anhui Province, Hefei 230601, PR China. Electronic address:
Background: Nonalcoholic fatty liver disease (NAFLD) is a major clinical and global public health issue, with no specific pharmacological treatment available. Currently, there is a lack of approved drugs for the clinical treatment of NAFLD. Large-leaf yellow tea polysaccharides (YTP) is a natural biomacromolecule with excellent prebiotic properties and significant therapeutic effects on multiple metabolic diseases.
View Article and Find Full Text PDFGenetic alteration of SLCO1B3 defines constitutional indocyanine green excretory defect in patients who underwent hepatectomy.
Hepatol Res
August 2024
Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Aim: Constitutional indocyanine green (ICG) excretory defects must be distinguished when assessing liver function. The absence of OATP1B3 expression due to homogenous alterations in the SLCO1B3 gene has been recently reported to induce ICG excretory defects; however, its association with the clinical examinations and the clinical implications of heterogeneous SLCO1B3 gene alteration remain unclear.
Methods: OATP1B3 expression was evaluated in 49 patients who underwent hepatectomy after evaluation of the ICG retention rate at 15 min (ICGR15) and technetium-99 m-galactosyl serum albumin (99mTc-GSA) hepatic scintigraphy.
A Novel Antioxidant, Hydrogen-Rich Coral Calcium Alters Gut Microbiome and Bile Acid Synthesis to Improve Methionine-and-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease.
Antioxidants (Basel)
June 2024
Department of Internal Medicine, Tainan Municipal Hospital (Managed by Show-Chwan Medical Care Corporation), Tainan 701, Taiwan.
Article Synopsis
- The incidence of non-alcoholic fatty liver disease (NAFLD) is rising, often linked to metabolic diseases and the risk of liver cancer, but effective treatments are lacking.
- Hydrogen-rich coral calcium (HRCC) was created as a more convenient alternative to hydrogen-rich water, with unknown effects on NAFLD.
- In a study, HRCC improved liver conditions in mice with NAFLD by reducing inflammation, enhancing antioxidant activity, altering gut microbiome composition, and increasing beneficial bile acid levels.
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