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Alginate-polylysine-alginate (APA) microencapsulated transgenic human amniotic epithelial cells ameliorate fibrosis in hypertrophic scars.

Inflamm Res

January 2025

Department of Burns and Cutaneous Surgery, Xijing Hospital, Air Force Medical University, No.127 Changle West Road, Xincheng District, Xi'an, 710032, Shaanxi, China.

Background: Hypertrophic scar (HS) is a severe skin fibrosis. Transplanting stem cells carrying anti-fibrotic cytokine genes, like interferon-gamma (IFN-γ), is a novel therapeutic strategy. Human amniotic epithelial cells (hAECs) are ideal seed cells and gene vectors.

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Fiber Bragg gratings (FBGs) inscribed by UV light and different femtosecond laser techniques (phase mask, point-by-point, and plane-by-plane) were exposed-in several irradiation cycles-to accumulated high doses of gamma rays (up to 124 MGy) and neutron fluence (8.7 × 10/cm) in a research-grade nuclear reactor. The FBG peak wavelengths were measured continuously in order to monitor radiation-induced shifts.

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To reveal the microstructural evolution and stress-strain distribution of 780 MPa-grade ferrite/martensite dual-phase steel during a uniaxial tensile deformation process, the plastic deformation behavior under uniaxial tension was studied using in situ EBSD and crystal plastic finite element method (CPFEM). The results showed that the geometrically necessary dislocations (GND) in ferrite accumulated continuously, which is conducive to the formation of grain boundaries, but the texture distribution did not change significantly. The average misorientation angle decreased and the proportion of low-angle grain boundaries increased with the increase of strain.

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Ultrasonic welding (USW) is considered one of the most suitable methods to join semi-crystalline carbon fiber-reinforced thermoplastics (CFRTPs). The degree of crystallinity (DoC) of the semi-crystalline resin will affect the ultrasonic welding process by affecting the mechanical properties of the base material. In addition, ultrasonic welding parameters will affect the joint performance by affecting the DoC of the welded material at the welding interface.

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Coffee Pulp from Azores: A Novel Phytochemical-Rich Food with Potential Anti-Diabetic Properties.

Foods

January 2025

Network of Chemistry and Technology/Associated Laboratory for Green Chemistry (REQUIMTE/LAQV), Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.

Coffee pulp, a by-product of wet coffee processing, shows significant potential in the food and health domains, but its real applications remain underexplored. This work investigated the chemical composition and bioactive properties of coffee pulp from São Miguel Island (Azores, Portugal). The studied coffee pulp exhibited high fiber content (52% dw), mostly insoluble; notable mineral levels (10.

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