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Preeclampsia Treatment Aspirin/Clampsilin: Oxidative Stress, sFlt-1/PIGF Soluble Tyrosine Kinase 1, and Placental Growth Factor Monitoring.
Int J Mol Sci
December 2024
Department of Medical Chemistry and Biochemistry, Medical Faculty, Trakia University, 11 Armeiska Str., 6000 Stara Zagora, Bulgaria.
The present study aimed to investigate and compare oxidative stress biomarkers and antioxidant enzyme activity in the serum of women at risk of developing preeclampsia (PE) to prevent adverse pregnancy outcomes through early intervention. Changes in soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) levels were measured between 11 and 13 gestational weeks (gw.) before the onset of preeclampsia and its associated complications.
View Article and Find Full Text PDFA Tale of Two Cysts: A Histopathological Case Report of Epithelial and Mesothelial Splenic Cysts.
Cureus
December 2024
Research Institute, Medical University of Pleven, Pleven, BGR.
Splenic cysts are rare medical conditions, and their incidence is dominated by parasitic types. Non-parasitic splenic cysts, whether true cysts (with a cellular lining of the cystic wall) or pseudocysts (without a cellular lining), are significantly rarer than parasitic ones. Their etiology is not fully established, with fetal remnant development, metaplasia, and mesothelial invagination being widely accepted possible mechanisms.
View Article and Find Full Text PDFNosocomial Bacterial Bronchopneumonia and SARS-CoV-2 Pneumonia in Patients with Traumatic Injuries: Imaging Aspects and Macroscopic and Microscopic Findings of Lung Tissue.
Diagnostics (Basel)
December 2024
Institute of Forensic Medicine Timisoara, 300041 Timisoara, Romania.
Background: Patients with traumatic injuries often represent the best hosts for healthcare-associated infections, especially pneumonia or bronchopneumonia. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic raised serious problems in the diagnosis and treatment of patients that had a SARS-CoV-2 infection and associated nosocomial bacterial bronchopneumonia. In forensic medicine, these aspects need to be considered when establishing the cause of death and the distinction between the two types of bronchopneumonia is of particular importance.
View Article and Find Full Text PDFA Rare Case of Cementoblastoma of the Second Right Maxillary Premolar in a 30-Year-Old Man.
Cureus
November 2024
Department of Pediatric Dentistry, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR.
Cementoblastoma is a benign odontogenic mesenchymal tumor characterized by cementum production. Cementoblastoma is considered a relatively rare neoplasm with a predilection to the posterior region of the mandible. The main clinical differential diagnoses include hypercementosis, cemento-osseous dysplasia, condensing osteitis, idiopathic osteosclerosis, osteoblastoma, odontoma, and osteosarcoma.
View Article and Find Full Text PDFUrothelial Carcinoma With Divergent Glandular Differentiation.
Cureus
October 2024
Pathology, Multiprofile Hospital for Active Treatment, Shumen, BGR.
Article Synopsis
- Divergent differentiation in urothelial carcinoma complicates accurate histopathological diagnosis, as traditional cancer features can be sparse, leading to potential oversights by inexperienced pathologists.
- Recognizing this differentiation is vital not only for establishing a correct diagnosis and preventing the false reporting of rare tumors but also because it influences the classification of the cancer as high-grade, impacting patient treatment and management.
- A case study of a male patient revealed a high-grade urothelial carcinoma with features resembling primarily colonic-type adenocarcinoma, showcasing the importance of identifying divergent differentiation to rule out metastasis from other organs.
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