It was established by a series of experiments with white Wistar rats that intraperitoneal injection of water extracts (infusions) of a mixed sample of dried algae (Cystosira barbata, Ulva lactica and Zostera nona) collected at the Bourgas coastal region, respectively leveled to an isotonic solution by use of 0.9% NaCl produces well expressed antiinflammatory effect in Caragina provoked oedema. The mixed sample of algae has LD0--0.250 g dry drug per kg body weight, LD'100--0.500 g/kg b. w. and LD50--0.407 g/kg b. w. The therapeutic index of the algae is relatively high -- LD50/U50+20.

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