The effect of forced cooling was studied as applied to the contents of ammonia, glutamine, glutaminic, asparaginic and alpha-amino butyric acids in the brain of sousliks woken-from hibernation. The cooling of the woken sousliks to the body temperature of 30, 20 and 25 degrees C decreased to some extent the ammonia content in the brain. A deeper hypothermia (10 degrees C) causes its 60,4% decrease as compared to the ammonia amount in woken animals. The cooling of the animals to 30, 25, 20 and 10 degrees C considerably decreases the contents of glutamine, glutaminic acid and GABA in the brain tissue.
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Int J Neurosci
February 2014
1Research Center for Sectional and Imaging Anatomy, Shandong University School of Medicine, Jinan, Shandong , China.
This study aims to investigate metabolic changes in frontal and parietal cortices in the 6-OHDA induced Parkinson's rats. Ratios of N-acetyl-aspartic acid/creatine (NAA/Cr), choline/creatine (Cho/Cr), and glumatic acid and glutamine glutaminic acid/creatine (Glx/Cr) of regions of interests (ROIs) in the frontal and parietal cortices, and the substantia nigra were analyzed. NAA/Cr, Cho/Cr and Glx/Cr in the frontal and parietal cortices in the lesion side did not show any significant differences two weeks after operation compared with the contralateral side (p > 0.
View Article and Find Full Text PDFZhonghua Yan Ke Za Zhi
October 2009
Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Objective: To explore the pathogenic mutation in a Chinese family with congenital aniridia.
Methods: It is a case-control study. All 21 members of the family underwent a comprehensive ophthalmic examination and family line investigation.
Wiad Parazytol
October 2006
Katedra Biologii i Parazytologii Lekarskiej, 90-436 Lódź, al. Kościuszki 4.
We have studied the capability of dissociation of 22 L-form aminoacids by 27 strains of fungi belonging to species: Candida, Cryptococcus, Geotrichum, Rhodotorula, Saccharomyces, Trichosporon. Fungal strains were cultured on agar medium with phenyl red and studied aminoacid. Disamination of an aminoacid by a fungus resulted in alkalisation of the medium and change of its colour from yellow to pink.
View Article and Find Full Text PDFMed Wieku Rozwoj
May 2006
Klinika Neonatologii, Akademia Medyczna, ul. Karowa 2, 00-315 Warszawa, Poland.
Introduction: Parenteral feeding is the basic way of nutrition in the first day of life in infants with very low birth weight. Due to its instability glutamine is not included in aminoacid solutions used for parenteral nutrition. Meanwhile glutamine is an important aminoacid, which plays a major role in the maturation of the gastrointestinal tract as well as the immunological system.
View Article and Find Full Text PDFThe basic scientific achievements of the Department of Biochemistry of Muscles organized at the Academy of Sciences of Ukrainian SSR in 1944 are presented in this short historical overview. The basic guidelines for activities in the scientific field are as follows: study of biochemical processes in the working muscles as well as during misfunctions and disabilities, processes of adenine nucleotides exchange and ammonia creation, biochemical characterization of Ca2+ and H+ transport through the plasma and sarcoplasmic reticulum membranes. It is shown that creatine and creatine phosphate as well as adenine nucleotide content and metabolism affect the muscle functioning, glycogen metabolism proceeds simultaneously with the lowering of content of inorganic phosphate.
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