AI Article Synopsis
- The study observed that 11 patients with Parkinson's disease experienced a significant reduction in pupillary diameter four hours after taking L-dopa.
- The observed miosis (constricted pupils) may be due to decreased noradrenaline release at sympathetic nerve endings.
- Another possibility discussed is that the effect could be linked to actions on the central nervous system.
Article Abstract
The pupillary diameter of 11 patients with Parkinson's disease was significantly decreased four hours after ingestion of L-dopa. It is suggested that this miosis may be caused by diminished noradrenaline output at sympathetic nerve endings, or alternatively by an action on the central nervous system.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1700778 | PMC |
| http://dx.doi.org/10.1136/bmj.2.5710.639 | DOI Listing |
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