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Trichoptysis: a pathognomonic presentation of anterior mediastinal teratoma.
BMJ Case Rep
January 2025
Surgical Oncology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Germ cell tumours are usually found in the gonads, while the most common extragonadal site is the anterior mediastinum. When these tumours involve the tracheobronchial tree, patients present with trichoptysis or coughing up of hair. We present a rare case of a woman who presented with trichoptysis and was evaluated and diagnosed with benign mature teratoma of the anterior mediastinum with bronchopulmonary involvement.
View Article and Find Full Text PDFGlypican-3 is a key tuner of the Hedgehog pathway in COPD.
Heliyon
January 2025
Université de Reims Champagne-Ardenne, INSERM, P3Cell UMR-S1250, Reims, France.
Hedgehog (HH) pathway is involved in pulmonary development and lung homeostasis. It orchestrates airway epithelial cell (AEC) differentiation and contributes to respiratory pathogenesis. The core elements Gli2, Smo, and Shh were found altered in the bronchial epithelium of patients with chronic obstructive pulmonary disease (COPD).
View Article and Find Full Text PDFRole of narrow band imaging in assessing bronchial mucosal hypervascularization in COVID-19 patients.
Respir Med Res
January 2025
Pneumology Department, University Hospital Centre Amiens-Picardie, Amiens, France; AGIR Unit, University Picardie Jules Vernes, Amiens, France.
Background: SARS-CoV-2 virus which targets the lung vasculature is supposed to affect both pulmonary and bronchial arteries. This study evaluated the tracheobronchial vascularization density observed with narrow band imaging (NBI) in patients hospitalized for COVID-19 pneumonia. To determine if the observed changes were specific of COVID-19 patients, the procedure was also performed in non-COVID-19 patients.
View Article and Find Full Text PDFAnalysis of pulmonary sequestration cases, based on the 11-year birth defects surveillance data of Changsha hospitals.
Sci Rep
January 2025
Office of the National Agency for Drug Clinical Trials, Changsha Hospital for Maternal, Child Health Care of Hunan Normal University, 416 Chengnan Dong Rd, Yuhua, Changsha, 410007, Hunan, China.
Pulmonary sequestration (PS) is a rare congenital malformation that is characterized by the absence of a connection between a portion of the lung tissue and the tracheobronchial tree, with blood supply from arteries throughout the body. Abnormal lung tissue cannot perform the normal gas exchange function. In the absence of timely diagnosis and early intervention, some cases may need labor induction, and some of the infants who survive may develop symptoms in childhood.
View Article and Find Full Text PDFMulti-disciplinary treatment of broncho-esophageal fistula in a high-risk single-lung patient.
J Cardiothorac Surg
January 2025
Section of Cardiothoracic Surgery, Department of Heart Disease, Haukeland University Hospital, Jonas Lies vei 65, 5021, Bergen, Norway.
Background: A broncho-esophageal fistula (BEF) is a medical and surgical disaster. Treatment of BEF is often limited to palliative stent treatment that may migrate or cause erosions and tissue necrosis. Surgical repair of BEF is the only established definite treatment.
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