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Antibiotics-induced pulmonary embolism: A disproportionality analysis in Food and Drug Administration database of Adverse Event Reporting System using data mining algorithms.
Perspect Clin Res
September 2024
Department of Pharmacy Practice, Faculty of Pharmacy, M. S. Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
Background: Antibiotics are among the most commonly prescribed drugs. Unnecessary use of antibiotics is particularly concerning because antibiotics may be associated with a number of adverse drug events.
Aim: The study was designed to detect the association between pulmonary embolism and antibiotics by disproportionality analysis in the Food and Drug Administration database of Adverse Event Reporting System (FAERS) using data mining algorithms (DMAs).
Atypical presentation and response to treatment in scrub typhus: a series of 2 cases.
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Department of Pediatrics, Manipal Tata Medical College and Tata Main Hospital, Jamshedpur, India.
Scrub typhus is an acute febrile illness caused by . It usually presents with high fever, lymphadenopathy, rash, organomegaly and an eschar formation at the site of the bite. Doxycycline is the drug of choice usually showing rapid defervescence, but rarely some cases does not respond.
View Article and Find Full Text PDFNovel D-Ribofuranosyl Tetrazoles: Synthesis, Characterization, In Vitro Antimicrobial Activity, and Computational Studies.
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Applied Chemistry and Environment Laboratory, Applied Bioorganic Chemistry Team, Faculty of Science, Ibn Zohr University, Agadir 80000, Morocco.
The goal of this study was to synthesize and evaluate new antimicrobial compounds. We specifically focused on the development of 2,5-disubstituted tetrazole derivatives containing the O-methyl-2,3-O-isopropylidene-(D)-ribofuranoside groups through N-alkylation reactions. The synthesized compounds were characterized using H and C nuclear magnetic resonance (NMR) spectroscopy.
View Article and Find Full Text PDFRisk assessment and photo-disinfection of antibiotic residues and antibiotic-resistant bacteria in water sources from Ede, Nigeria.
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African Centre of Excellence for Water and Environmental Research (ACEWATER), Redeemer's University, Osun State, Nigeria.
Environmental antibiotic residues (EARs) and antibiotic-resistant bacteria (ARB) are known to contribute to global antimicrobial resistance (AMR). This study investigated EAR levels in selected wells, river, abattoir wastewater, bottled water and sachet water from Ede, Nigeria. Ecological risk quotient (RQ) and health risk (Hazard quotient) of the levels of these EARs, ARB and multidrug-resistant bacteria (MDR) with their antibiotic resistance were calculated.
View Article and Find Full Text PDFChicken meat is a major source of foodborne salmonellosis. In Japan, fluoroquinolones and third-generation cephalosporins are the first- and second-choice treatments for Salmonella gastroenteritis, respectively. We investigated the prevalence and antimicrobial resistance of Salmonella in 154 chicken meat products from Hokkaido (42), Tohoku (45), Kanto (5), and Kyushu (62), Japan.
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