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Evaluation of variations in predominant gut microbiota members in inflammatory bowel disease using real-time PCR.
Mol Biol Rep
January 2025
Department of Internal Medicine, Faculty of Medicine, Urmia University of Medical Sciences, Imam Khomeini Hospital, Urmia, Iran.
Inflammatory Bowel Disease (IBD) is a persistent ailment that impacts many individuals worldwide. The interaction between the immune system and gut microbiome is thought to influence IBD development. This study aimed to assess some microbiota in IBD patients compared to healthy individuals.
View Article and Find Full Text PDFMicrobiome transplants may not improve health and longevity in Drosophila melanogaster.
Biol Open
January 2025
Department of Biological Sciences, Augusta University, Augusta, GA 30912, USA.
The gut microbiome, which is composed of bacteria, viruses, and fungi, and is involved in multiple essential physiological processes, changes measurably as a person ages, and can be associated with negative health outcomes. Microbiome transplants have been proposed as a method to improve gut function and reduce or reverse multiple disorders, including age-related diseases. Here, we take advantage of the laboratory model organism, Drosophila melanogaster, to test the effects of transplanting the microbiome of a young fly into middle-aged flies, across multiple genetic backgrounds and both sexes, to test whether age-related lifespan could be increased, and late-life physical health declines mitigated.
View Article and Find Full Text PDFComparing to three other enteric pathogens in OligoMM mice reveals pathogen-specific host and microbiota responses.
Gut Microbes
December 2025
Institute of Microbiology, Department of Biology, ETH Zurich, Zurich, Switzerland.
, non-typhoidal spp., and enteropathogenic/enterohemorrhagic (EPEC/EHEC) are leading causes of food-borne illness worldwide. has been used to model EPEC and EHEC infection in mice.
View Article and Find Full Text PDFHuman milk oligosaccharides: bridging the gap in intestinal microbiota between mothers and infants.
Front Cell Infect Microbiol
January 2025
Department of Traditional Chinese Medicine, Shanghai Fourth People's Hospital Affiliated to Tongji University, Shanghai, China.
Breast milk is an essential source of infant nutrition. It is also a vital determinant of the structure and function of the infant intestinal microbial community, and it connects the mother and infant intestinal microbiota. Human milk oligosaccharides (HMOs) are a critical component in breast milk.
View Article and Find Full Text PDFAmmonia and hydrogen sulfide - new insights into gut microbiota and male infertility through meta-analysis.
Front Cell Infect Microbiol
January 2025
College of Environmental and Life Sciences, Murdoch University, Perth, WA, Australia.
Background: Ammonia (NH) and hydrogen sulfide (HS) are produced during digestion in the human gut, yet the impact of these internally generated gases on male reproduction have received limited attention in scientific research.
Methods: We systematically reviewed 935 scientific publications, spanning from 1947 to 2023, focusing on external or internal NH and/or HS, male infertility, and gut microbiota. Meta-analysis was conducted to evaluate the summary relative risk (RR) and 95% confidence intervals (CIs) of combined studies.
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