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Comparison of intravoxel incoherent motion and diffusion kurtosis imaging and 18- FDG PET/CT in response assessment in rectosigmoid carcinoma.
Abdom Radiol (NY)
November 2024
All India Institute of Medical Sciences, New Delhi, India.
Article Synopsis
- The study aimed to evaluate how well intravoxel incoherent motion and diffusion kurtosis imaging (IVIM-DKI) can assess rectosigmoid carcinoma response to chemo-radiotherapy (CRT), compared to standard 18-FDG PET/CT imaging.
- A cohort of 30 rectosigmoid cancer patients had both IVIM-DKI MRI and follow-up 18-FDG PET/CT scans before and after CRT; various imaging parameters were analyzed to correlate with treatment response using RECIST criteria.
- Results showed significant changes in IVIM-DKI parameters after therapy, but 18-FDG PET/CT was more effective in evaluating treatment response and tumor burden, with TLG changes being particularly indicative of patient outcomes.
Study of Comparison of Magnetic Resonance Imaging with Surgical and Pathological features in Carcinoma Rectum Patients.
Indian J Surg Oncol
June 2024
Department of Radiodiagnosis, Acharya Harihar Regional Cancer Centre, Cuttack, India.
Colorectal cancer is the second-most common cancer in the females and third-most common cancer in males worldwide and it is the second-most common cause of mortality. In India, colorectal cancer is the fifth-most common cancer overall, constituting 6.3%.
View Article and Find Full Text PDFFeasibility of laparoscopic Visceral-Peritoneal Debulking (L-VPD) in patients with stage III-IV ovarian cancer: the ULTRA-LAP trial pilot study.
J Gynecol Oncol
March 2024
Division of Women's and Children Health, Department of Gynecology and Obstetrics, Padova University Hospital, Padova, Italy.
Objective: A non-randomized prospective clinical trial (ULTRA-LAP) was registered to test safety, side effects and efficacy of laparoscopic Visceral-Peritoneal Debulking (L-VPD) in patients with stage III-IV ovarian cancer (OC). A pilot study was designed to identify which OC patients are suitable to undergo L-VPD.
Methods: Between March 2016 and October 2021, all consecutive patients with OC underwent exploratory laparoscopy (EXL).
Synchronous Recto-Sigmoid Colorectal Carcinomas With Microsatellite Instability and an Activating PIK3CA Mutation.
J Investig Med High Impact Case Rep
August 2022
University of Florida, Gainesville, FL, USA.
Synchronous colorectal cancer is a rare subtype of colorectal carcinoma defined by the presence of 2 or more primary tumors simultaneously or within 6 months of initial detection. The overall impact of a synchronous presentation on prognosis is not yet clear. Surgical resection is the primary treatment.
View Article and Find Full Text PDFPrognostic Impact of Upfront Surgery for Locally Advanced Upper Rectal Adenocarcinoma.
Anticancer Res
January 2022
Department of Digestive, Oncological, Endocrine, Hepato-Biliary, Pancreatic and Liver Transplant Surgery, Trousseau Hospital, Chambray Les Tours, France
Background/aim: Impact of neoadjuvant chemoradiotherapy (CRT) in locally advanced upper rectal adenocarcinoma (LAURC) is debated. The aim of this study was to compare outcomes between LAURC and locally advanced sigmoid and recto-sigmoid junction cancer (LASC).
Patients And Methods: This retrospective study included 149 consecutive patients [42 CRT/LAURC, 16 upfront surgery (US/LAURC) and 91 LASC].
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