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Enhanced pathogen identification among patients with clinically suspected meningitis.
S Afr J Infect Dis
December 2024
Division of Medical Microbiology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Background: Delayed or incorrect treatment of meningitis may result in adverse patient outcomes. However, laboratory testing in resource-limited settings is often limited to conventional diagnostic methods. We explored the utility of syndromic molecular assays for diagnosis.
View Article and Find Full Text PDFThe International System for Serous Fluid Cytopathology (TIS) survey in preparation for TIS 2.0.
J Am Soc Cytopathol
December 2024
Department of Cellular Pathology, Guy's & St. Thomas' NHS Foundation Trust, London, UK.
Introduction: The International System for Serous Fluid Cytopathology (TIS) has gained acceptance and has led to literature validating original concepts and suggesting refinements. In preparation for the second edition of TIS, editors generated a survey to solicit experience with and opinions about TIS.
Materials And Methods: An online survey available from March 8 to June 15, 2024, included 56 questions, offered in 7 languages, related to the practice of serous fluid cytopathology.
Introduction Acute lymphoblastic leukemia (ALL) has suboptimal survival rates for adolescents and young adults (AYA) as compared to children. Very limited studies have been conducted on AYA patients in India. This study aimed to identify the cytogenetic and immunophenotype characteristics of B-cell ALL (B-ALL) in AYA patients and determine its correlation with clinicopathological parameters in the Southern India region.
View Article and Find Full Text PDFAnalysis of neuraminidase activity of human parainfluenza viruses using enzyme-linked lectin assay and BTP3-Neu5Ac assay.
Microbiol Immunol
November 2024
Virus Research Center, Clinical Research Division, Sendai Medical Center, National Hospital Organization, Sendai, Japan.
Human parainfluenza viruses (hPIVs) are causative agents of upper and lower respiratory tract infections and they have four serotypes. The virion surface displays hemagglutinin-neuraminidase (HN), having hemagglutinating (HA) and neuraminidase (NA) activities in a single molecule. The HA activity binds the virion to sialic acid on the viral receptor on host cells and the NA releases the progeny viruses from the cell surface.
View Article and Find Full Text PDFClinical and diagnostic evaluation of a wild ocelot () specimen.
Open Vet J
August 2024
Grupo de Investigación en Medicina Veterinaria (GINVER), Corporación Universitaria Remington, Medellín, Colombia.
Background: Monitoring the health of wild animals under the principles of one health contributes to the prevention of diseases and the preservation of human and animal health, thus contributing to the conservation of species.
Aim: The current study describes the clinical and paraclinical status of an ocelot () captured in Buriticá, Antioquia, Colombia, for research purposes with the aim of contributing to the construction of animal health reference values in the wild, considering the scarcity of published data for the country on capture, management, and paraclinical parameters related to this species.
Methods: For this, hematological parameters, blood chemistry, urine cytochemical analyses, and coprological examinations were carried out.
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