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Evolutionary insights into gut acidification: Invertebrate-like mechanisms in the basal vertebrate hagfish.
J Exp Biol
January 2025
Department of Biological Sciences, University of Alberta, 116 St and 85 Ave, Edmonton, AB T6G 2R3, Canada.
Acidification is a key component of digestion throughout metazoans. The gut digestive fluid of many invertebrates is acidified by the vesicular-type H+-ATPase (VHA). In contrast, vertebrates generate acidic gut fluids using the gastric H+/K+-ATPase (HKA); an evolutionary innovation linked with the appearance of a true stomach that greatly improves digestion, absorption, and immune function.
View Article and Find Full Text PDFLow-grade mucinous neoplasm originating from intestinal duplication: a case report and review of the literature.
World J Surg Oncol
January 2025
Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, 158 Shangtang Road, Hangzhou, Zhejiang, 310014, China.
Background: Low-grade mucinous neoplasms typically originate from the appendix and are characterized by a lining of low-grade mucus-secreting columnar epithelial cells and smooth muscle. However, atypical origins can occur, as demonstrated in this case report.
Case Presentation: We present a case involving a 33-year-old male who, upon physical examination, was found to have an abdominal mass.
Detection of small intestine duplication in a 16-year-old girl using small bowel enteroscopy without balloon assistance.
Endoscopy
December 2025
Gastroenterology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Small bowel duplication cyst in the pediatric population-when to operate?
Pediatr Surg Int
January 2025
Department of Pediatric and Adolescent Surgery, Schneider Children's Medical Center of Israel, 14 Kaplan St, Petah Tiqwa, Israel.
Introduction: AIM: The aim of the study is to determine the optimal timing for surgery in patients with small bowel duplications.
Methods: A retrospective cohort study, including all patients younger than 18 years who were diagnosed with small bowel duplications from 2013 until 2024 in a single tertiary medical center, was performed. Patients' demographics, duplication size and location, pathological results, and clinical outcomes were collected.
Evolutionary dynamics and regulatory site analysis of AMP family genes in cattle and sheep.
Int J Biol Macromol
December 2024
College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, Gansu, China.; College of Veterinary Medicine, Northwest Agriculture & Forestry University, Yangling, Shanxi, 712100, China. Electronic address:
Background: Ruminants possess a rich repository of natural antimicrobial peptides(AMPs) within their bodies, surpassing those found in humans and mice. These peptides, including Defensin, Cathelicidin, and Lysozyme, are integral to the body's innate and adaptive immune responses and represent promising alternatives to antibiotics with significant application potential.
Results: In the present study, we conducted a systematic analysis of 40 Defensins, 38 Cathelicidins, and 61 Lysozymes in cattle and sheep.
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