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A rapid literature review of the impact of penicillin allergy on antibiotic resistance.
JAC Antimicrob Resist
February 2025
Department of Microbiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Background: Antimicrobial resistance (AMR) is caused by the use and misuse of antibiotics. AMR is a global health concern, to which penicillin allergy (penA) labels appear to contribute. Patients who have penA labels are treated with non-penicillin antibiotics and receive more antibiotics when compared with patients without penA.
View Article and Find Full Text PDFAssociation between penicillin allergy labels and serious adverse events in hospitalized patients: a systematic review and meta-analysis.
Front Pharmacol
January 2025
Clinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Background: To date, several studies have demonstrated that erroneous labeling of Penicillin allergy (PAL) can significantly impact treatment options and result in adverse clinical outcomes, while other studies have reported no negative effects. Therefore, to systematically evaluate these effects and investigate the association between adverse clinical outcomes and the Penicillin label, we conducted this meta-analysis.
Method: Searches were conducted in the PubMed, Embase, Cochrane Library, and Web of Science databases from inception to 13 July 2024.
Protective immunity induced by a novel P1 adhesin C-terminal anchored mRNA vaccine against infection in BALB/c mice.
Microbiol Spectr
January 2025
Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical College, Institute of Pathogenic Biology, University of South China, Hengyang, China.
(Mp), a unique pathogen devoid of a cell wall, is naturally impervious to penicillin antibiotics. This bacterium is the causative agent of pneumonia, an acute pulmonary affliction marked by interstitial lung damage. Non-macrolide medications may have potential adverse effects on the developmental trajectory of children, thereby establishing macrolides as the preferred treatment for in pediatric patients.
View Article and Find Full Text PDFAntimicrobial use in animal farms in Egypt: rates, patterns, and determinants.
J Egypt Public Health Assoc
January 2025
Faculty of Pharmacy, Alamein International University, Matrouh, Egypt.
Background: While antimicrobial use (AMU) in human healthcare has received significant attention as a key driver of antimicrobial resistance (AMR), less emphasis has been placed on AMU practices and attitudes in animal husbandry. To address this gap, this study examines the patterns and underlying drivers of AMU on animal farms.
Methods: A survey instrument was distributed to farm staff in 150 animal farms across 15 Egyptian governorates.
Unusual Genomic and Biochemical Features of sp. nov-A Novel Bacterial Species Isolated from Anthill Soil.
Int J Mol Sci
December 2024
Faculty of Soil Science, M.V. Lomonosov Moscow State University, Leninskie Gory, 1, 119991 Moscow, Russia.
The black garden ant () is a widely distributed species across Europe, North America, and North Africa, playing a pivotal role in ecological processes within its diverse habitats. However, the microbiome associated with remains poorly investigated. In the present study, we isolated a novel species, , from the soil of the anthill.
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