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Postural control in episodic ataxia type 2: no evidence for increased vestibular excitability.
Eur J Neurol
January 2025
Department of Neurology, University Hospital Schleswig-Holstein, Lübeck, Germany.
Background And Purpose: Patients with episodic ataxia type 2 (EA2) suffer from recurrent paroxysmal episodes of vertigo and oscillopsia. Pathophysiologically, altered neuronal excitability has been suspected. Vestibular excitability in 22 EA2 patients and 22 age-matched healthy participants was compared.
View Article and Find Full Text PDFCanine idiopathic generalized tremor syndrome, immune-mediated?
Front Vet Sci
September 2024
Department of Small Animal Medicine and Surgery, University of Veterinary Medicine, Hannover, Germany.
Idiopathic generalized tremor syndrome is a disorder characterized by an acute onset of full-body tremors, sometimes accompanied by vestibulo-cerebellar signs, that is responsive to treatment with corticosteroids. Although considered to have an overall good outcome, relapsing and persistent mild clinical signs have been described. So far, little is known about the etiopathology of this syndrome, but it is believed to have an immune-mediated origin.
View Article and Find Full Text PDF[What's behind cerebellar dizziness? - News on diagnosis and therapy].
Laryngorhinootologie
May 2024
Neurologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, München, Germany.
Article Synopsis
- Vertigo and dizziness can be caused by problems in the brain's balance center and affect around 10% of people visiting clinics for these issues.* -
- There are three main types of symptoms: constant dizziness, episodes of dizziness, or sudden onset of dizziness, with many patients experiencing continuous feelings of vertigo.* -
- Doctors use a detailed history and special tests on eye movement to help diagnose the problem, and additional tests can help check balance and the risk of falling.*
The gait disorder in primary orthostatic tremor.
J Neurol
December 2020
German Center for Vertigo and Balance Disorders, University Hospital, LMU Munich, Munich, Germany.
Objective: To uncover possible impairments of walking and dynamic postural stability in patients with primary orthostatic tremor (OT).
Methods: Spatiotemporal gait characteristics were quantified in 18 patients with primary OT (mean age 70.5 ± 5.
Schmahmann's syndrome - identification of the third cornerstone of clinical ataxiology.
Cerebellum Ataxias
September 2015
Clinical and Experimental Neurolinguistics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium ; Department of Neurology and Memory Clinic, ZNA General Hospital Middelheim, Lindendreef 1, 2020 Antwerp, Belgium.
Schmahmann's syndrome represents a novel clinical condition consisting of a constellation of cognitive and affective deficits following cerebellar disease. The complex was first described in 1998 as cerebellar cognitive affective syndrome (CCAS) on the basis of a careful neurological examination, detailed bedside mental state tests, neuropsychological investigations and anatomical neuroimaging of a group of 20 patients with focal cerebellar disorders. The syndrome was characterized by four clusters of symptoms including: (a) impairment of executive functions such as planning, set-shifting, verbal fluency, abstract reasoning and working memory, (b) impaired visuo-spatial cognition, (c) personality changes with blunting of affect or abnormal behaviour, and (d) language deficits including agrammatism, wordfinding disturbances, disruption of language dynamics and dysprosodia.
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