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Assessment of smartphone-based active distraction in association with audioanalgesia for overcoming airotor-related anxiety in children: a randomized controlled trial.
BMC Res Notes
January 2025
Manipal Academy of Higher Education, Manipal, Karnataka, India.
Background: Most children experience distress while visiting a dentist, above which the sound of the airotor and suction machine results in fear and difficulty in performing further procedures.
Methods: This was a randomized controlled parallel-group study of 40 children aged 6-13 years who required cavity preparation via the airotor. The children were randomly allocated to either Group 1 (Piano music app; active distraction combined with audio analgesia) or Group 2 (basic behavioural guidance alone).
Low-exhaustion peripheral circulating γδ T cells serve as a biomarker for predicting the clinical benefit rate of non-small cell lung cancer (NSCLC) patients to chemotherapy or targeted therapy: a single-center retrospective study.
BMC Cancer
January 2025
Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.
Background: Multiple studies have demonstrated that the abundance and functionality of γδ T cells are favorable prognostic indicators for prolonged survival in cancer patients. However, the association between the immunophenotype of circulating γδ T cells and the therapeutic response in NSCLC patients undergoing chemotherapy or targeted therapy remains unclear.
Methods: Patients with EGFR wild-type (EGFR-WT) or mutant (EGFR-Mut) non-small cell lung cancer (NSCLC), diagnosed between January 2020 and January 2024, were included in this study.
Association between cardiovascular health and osteoporotic fractures: a national population-based study.
Sci Rep
January 2025
Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, NO. 172 Tong Zi Po Road, Yuelu District, Changsha, 410006, Hunan, China.
Osteoporotic fractures are a major public health concern, particularly among the aging population, as they significantly contribute to morbidity, mortality, and reduced quality of life. While cardiovascular health (CVH) has traditionally been linked to cardiovascular disease outcomes, emerging evidence suggests it may also influence bone health. This study investigates the association between CVH, as measured by the Life's Essential 8 (LE8) score, and the prevalence of osteoporotic fractures in U.
View Article and Find Full Text PDFComparison of laparoscopic performance using low-cost laparoscopy simulators versus state-of-the-art simulators: a multi-center prospective, randomized crossover trial.
Surg Endosc
January 2025
Department of Visceral, Thoracic and Vascular Surgery, Faculty of Medicine, University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Fetscherstraße 74, 01307, Dresden, Germany.
Introduction: Simulator training is an efficient method for the development of basic laparoscopic skills. We aimed to investigate if low-cost simulators are comparable to more expensive box trainers regarding surgeons usability, likability, and performance.
Methods: This multi-center, randomized crossover study included 16 medical students, seven abdominal surgeons, and seven urological surgeons.
3D evaluation of changes in mandibular condyle morphology following orthognathic surgery in patients with maxillomandibular asymmetry: A retrospective study.
J Craniomaxillofac Surg
January 2025
Ankara University, Faculty of Dentistry, Department of Dentomaxillofacial Radiology, Ankara, Turkey.
Symmetry is integral for the balance and function of the craniofacial complex and making precise diagnosis of asymmetric craniofacial structures is crucial for treatment planning. This study focuses on maxillomandibular asymmetry, examining its impact on condylar resorption and trabecular bone morphology changes following orthognathic surgery. Cone-beam computed tomography (CBCT) scans of patients with and without asymmetry were analyzed pre- and post-surgery.
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