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Abnormal in vitro development of ovarian follicles explanted from mice exposed to tetrachlorvinphos.
Reprod Toxicol
October 1994
Department of Reproductive Biology, German Primate Center, Göttingen.
A system of mouse ovarian follicle culture in which follicles can be grown from a preantral stage of development through antral formation has been developed and modified recently by Nayudu and colleagues. Follicles have been shown to grow in this culture system at a relatively constant rate and show responsiveness to LH at the end of the culture by ovulation of mature oocytes. Reported here are the distinctly different in vitro growth patterns of follicles explanted from 22- to 24-day-old mice during a period when the colony was being treated for skin parasites with tetrachlorvinphos (TCVP) (Rabond).
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