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sICAM-1 concentrations are associated with inflammation in contralateral carotid plaque in patients with ischemic stroke.
Clin Investig Arterioscler
August 2024
Cardiovascular Biochemistry, Cardiovascular Biochemistry, Research Institute Sant Pau (Institut de Recerca Sant Pau, IR Sant Pau), Barcelona, Spain; CIBER of Diabetes and Metabolic Diseases (CIBERDEM), Madrid, Spain. Electronic address:
Background: Atherosclerotic plaques in the internal carotid artery are responsible for more than 15% of ischemic strokes. Carotid F-fluorodeoxyglucose positron emission tomography (F-FDG PET) detects plaque inflammation. Plasma ICAM-1 and LRP1 concentrations have been associated with inflammation in ipsilateral carotid plaque.
View Article and Find Full Text PDFSerum neuregulin 1 in relation to ventricular function and subclinical atherosclerosis in type 2 diabetes patients.
Endocrinol Diabetes Nutr (Engl Ed)
December 2023
Department of Biochemistry and Molecular Biology, Faculty of Pharmacy for Boys, Al-Azhar University, Nasr City, 11231 Cairo, Egypt. Electronic address:
Background And Aims: Neuregulin 1 (NRG-1) is one of the members of the epidermal growth factors proteins. The present study provides novel insights into the relationship between serum levels of NRG-1 and insulin resistance, subclinical atherosclerosis and cardiac dysfunction that occur in type 2 diabetes (T2D).
Methods: The study included 50 patients with T2D and 40 healthy age- and gender-matched controls.
Evaluation of the relationship between atherosclerosis and Helicobacter pylori infection with measurement of growth differentiation factor 15 and atherosclerosis indicators in adults with no comorbidity.
Clin Investig Arterioscler
March 2024
Department of Internal Medicine, Kayseri City Training and Research Hospital, Kayseri, Turkey. Electronic address:
Background: The aim of this study was to investigate presence of subclinical atherosclerosis by measuring carotid intima-media thickness (CIMT) in patients with Helicobacter pylori (HP) and to assess effects of HP on atherosclerosis by evaluating markers of atherosclerosis and blood growth differentiation factor (GDF-15) levels.
Materials And Methods: This cross-sectional study included 59 patients without comorbid disease who had HP and 30 healthy controls without HP in upper endoscopic biopsy. In order to assess atherosclerosis, the CIMT measurement was performed by sonography.
The association of decreased testosterone with atherosclerosis and inflammation in male predialysis patients with chronic kidney disease.
Clin Investig Arterioscler
July 2021
The Department of Internal Medicine, Konya Health Application and Research Center, University of Health Sciences, Konya, Turkey.
Purpose: To investigate the frequency of hypogonadism and its relationship to inflammation and carotid intima-media thickness (CIMT) in male patients with predialysis chronic kidney disease (CKD).
Methods: A total of 105 patients with CKD, 55 (52.4%) as stage 3, 33 (31.
Untargeted Lipidomics Reveals a Specific Enrichment in Plasmalogens in Epicardial Adipose Tissue and a Specific Signature in Coronary Artery Disease.
Arterioscler Thromb Vasc Biol
April 2020
Aix-Marseille University, INSERM, INRAE, C2VN, France (A.D., P.A., L.S., R.V., S.B., J.C.M., B.G.).
Objective: Epicardial adipose tissue (EAT) is an active endocrine organ that could contribute to the pathophysiology of coronary artery disease (CAD) through the paracrine release of proatherogenic mediators. Numerous works have analyzed the inflammatory signature of EAT, but scarce informations on its lipidome are available. Our objective was first to study the differences between EAT and subcutaneous adipose tissue (SAT) lipidomes and second to identify the specific untargeted lipidomic signatures of EAT and SAT in CAD.
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