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Background: This study explores the value of interlobar fissure semilunar sign(IFSS) based on multifactor joint analysis in predicting the invasiveness of ground glass nodules(GGNs) with interlobar fissure attachment in the lungs.

Methods: This was a retrospective analysis of clinical data and CT images of 203 GGNs attached to the interlobar fissures confirmed by surgery and pathology. According to pathological results, those GGNs were divided into three groups: glandular precursor lesion (atypical adenomatous hyperplasia/adenocarcinoma in situ), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IAC).

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Background: A screening tool was devised to aid the diagnosis and treatment of ground-glass nodules (GGNs).

Methods: The current ambispective cohort study included retrospective collation of 20 variables synthesizing a patient's clinical characteristics, serum tumor markers, and CT results, which allowed division into noninvasive (benign, atypical adenomatous hyperplasia, and adenocarcinoma in situ) and invasive (minimally invasive and invasive adenocarcinomas) tumors to build a prediction nomogram and GGN screening scale. The model was verified internally.

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Article Synopsis
  • * Results showed that children with CAP had higher white blood cell counts, more lung abnormalities detectable via ultrasound, and significant differences in lung ultrasound scores (LUS) compared to healthy children.
  • * The findings suggest that lung ultrasound is a reliable diagnostic tool for CAP, with its results closely linked to serum procalcitonin levels and pediatric critical illness scores, demonstrating high sensitivity and specificity.
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Adenosquamous Carcinoma of the Lung: Survival, Radiologic Findings, PD-L1, and Driver Mutations.

J Clin Med

September 2024

Department of Thoracic Surgery, Clinic Floridsdorf, Vienna Healthcare Group, Bruenner Straße 68, 1210 Vienna, Austria.

Adenosquamous carcinoma of the lung (ASC) is a rare non-small-cell lung cancer (NSCLC) subtype combining components of squamous cell carcinoma (SCC) and adenocarcinoma (AC). Data on ASC, particularly in Caucasian populations, are limited. We reviewed clinicopathological and radiological characteristics of ASC patients diagnosed between 1996 and 2023.

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Background: The preoperative determination of visceral pleural invasion (VPI) in patients with malignant solitary pulmonary nodules (SPNs) is essential for determining the surgical range and selecting adjuvant chemotherapy.

Objectives: This study aimed to systematically investigate risk factors of VPI in patients with SPN and construct a preoperative predictive model for such patients.

Design: This is a retrospective study.

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